Adjuvant immunotherapy of C6 glioma in rats with pertussis toxin

Mario Orozco-Morales; Francisco-Javier Sánchez-García; Patricia Guevara-Salazar; Oscar Arrieta; Norma Y. Hernández-Pedro; Aurora Sánchez-García; Rodolfo Perez-Madrigal; Edgar Rangel-López; Benjamín Pineda; Julio Sotelo

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Adjuvant immunotherapy of C6 glioma in rats with pertussis toxin

机译：百日咳毒素大鼠C6胶质瘤的辅助免疫治疗

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In spite of the recent advances in surgery and antitumor drugs, the brain tumors, like glioblastoma, have shown a poor prognosis. The aim of this study was to determine the effect of pertussis toxin (PTx) as immunomodulatory molecule on glial tumors induced by C6 glioma cells.

机译：尽管最近在外科手术和抗肿瘤药物方面取得了进展，但脑肿瘤如胶质母细胞瘤的预后较差。这项研究的目的是确定百日咳毒素（PTx）作为免疫调节分子对C6胶质瘤细胞诱导的神经胶质瘤的作用。

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来源
《Journal of Cancer Research and Clinical Oncology》 |2012年第1期|p.23-33|共11页
作者
Mario Orozco-Morales; Francisco-Javier Sánchez-García; Patricia Guevara-Salazar; Oscar Arrieta; Norma Y. Hernández-Pedro; Aurora Sánchez-García; Rodolfo Perez-Madrigal; Edgar Rangel-López; Benjamín Pineda; Julio Sotelo;
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作者单位

Immunoregulation Unit from Instituto Politecnico Nacional, Mexico City, Mexico;

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正文语种 eng
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关键词
Pertussis toxin; Glioblastoma multiforme; Immunotherapeutic; Regulatory T cells; C6 glioma;

机译：百日咳毒素;多形胶质母细胞瘤;免疫治疗;调节性T细胞;C6神经胶质瘤;

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1. Adjuvant immunotherapy of C6 glioma in rats with pertussis toxin [J] . Orozco-MoralesM., Sánchez-GarcíaF.-J., Guevara-SalazarP., Journal of Cancer Research and Clinical Oncology . 2012,第1期

机译：百日咳毒素大鼠C6胶质瘤的辅助免疫治疗
2. Pertussis toxin treatment prevents 5-HT(5a) receptor-mediated inhibition of cyclic AMP accumulation in rat C6 glioma cells. [J] . Thomas EA, Matli JR, Hu JL, Journal of Neuroscience Research . 2000,第1期

机译：百日咳毒素治疗可防止5-HT（5a）受体介导的大鼠C6胶质瘤细胞中环AMP积累的抑制。
3. Foetal-calf serum stimulates a pertussis-toxin-sensitive high-affinity GTPase activity in rat glioma C6 BU1 cells [J] . G Milligan The biochemical journal . 1987,第2期

机译：胎牛血清刺激大鼠神经胶质瘤C6 BU1细胞对百日咳毒素敏感的高亲和力GTPase活性
4. Penetration of PLGA nanoparticles into the intracranial rat C6 Glioma: Influence of surfactant coating - (PPT) [C] . Yulia M. Alinovskaya, Nadezhda Osipova, Olga Maksimenko, Nanotechnology in Medicine: From Molecules to Humans Conference . 2017

机译：PLGA纳米粒子渗透到颅内大鼠C6胶质瘤中：表面活性剂涂层的影响 - （PPT）
5. Targeting the Disialoganglioside GD2 with Chimeric Antigen Receptor T Cells for Immunotherapy in Diffuse Midline Gliomas, and Exploration of Neuron-OPC Synaptic Connectivity in the Context of Adaptive Myelination [D] . Mount, Christopher W. 2020

机译：用嵌合抗原受体T细胞靶向Diaialoganglioside GD2，用于在弥漫性中线胶质瘤中的免疫疗法，以及在适应性髓鞘中的背景下探索神经元-Popaptic连通性
6. Foetal-calf serum stimulates a pertussis-toxin-sensitive high-affinity GTPase activity in rat glioma C6 BU1 cells. [O] . G Milligan 1987

机译：胎牛血清刺激大鼠神经胶质瘤C6 BU1细胞中对百日咳毒素敏感的高亲和力GTPase活性。
7. The GTP-binding regulatory proteins of neuroblastoma × glioma, NG108-15, and glioma, C6, cells Immunochemical evidence of a pertussis toxin substrate that is neither Ni nor No [O] . Milligan Graeme, Gierschik Peter, Spiegel Allen M., 1986

机译：神经母细胞瘤×神经胶质瘤NG108-15和神经胶质瘤C6的GTP结合调节蛋白细胞百日咳毒素底物既不是镍也不是否的免疫化学证据

Adjuvant immunotherapy of C6 glioma in rats with pertussis toxin

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