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Stimulus features, resetting curves, and the dependence on adaptation

机译:刺激特征,复位曲线以及对适应的依赖性

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We derive a formula that relates the spike-triggered covariance (STC) to the phase resetting curve (PRC) of a neural oscillator. We use this to show how changes in the shape of the PRC alter the sensitivity of the neuron to different stimulus features, which are the eigenvectors of the STC. We compute the PRC and STC for some biophysical models. We compare the STCs and their spectral properties for a two-parameter family of PRCs. Surprisingly, the skew of the PRC has a larger effect on the spectrum and shape of the STC than does the bimodality of the PRC (which plays a large role in synchronization properties). Finally, we relate the STC directly to the spike-triggered average and apply this theory to an olfactory bulb mitral cell recording.
机译:我们导出了一个公式,该公式将尖峰触发的协方差(STC)与神经振荡器的相位重置曲线(PRC)相关联。我们使用它来显示PRC形状的变化如何改变神经元对不同刺激特征(STC的特征向量)的敏感性。我们为某些生物物理模型计算PRC和STC。我们比较了两参数PRC系列的STC及其光谱特性。令人惊讶的是,PRC的偏斜对STC的频谱和形状的影响大于PRC的双峰(在同步特性中起很大作用)。最后,我们将STC直接与尖峰触发的平均值相关联,并将该理论应用于嗅球二尖瓣细胞记录。

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