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首页> 外文期刊>Journal of Computational Neuroscience >Stimulus-invariant processing and spectrotemporal reverse correlation in primary auditory cortex
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Stimulus-invariant processing and spectrotemporal reverse correlation in primary auditory cortex

机译:初级听觉皮层的刺激不变处理和光谱时间反向相关

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The spectrotemporal receptive field (STRF) provides a versatile and integrated, spectral and temporal, functional characterization of single cells in primary auditory cortex (AI). In this paper, we explore the origin of, and relationship between, different ways of measuring and analyzing an STRF. We demonstrate that STRFs measured using a spectrotemporally diverse array of broadband stimuli-such as dynamic ripples, spectrotemporally white noise, and temporally orthogonal ripple combinations (TORCs)-are very similar, confirming earlier findings that the STRF is a robust linear descriptor of the cell. We also present a new deterministic analysis framework that employs the Fourier series to describe the spectrotemporal modulations contained in the stimuli and responses. Additional insights into the STRF measurements, including the nature and interpretation of measurement errors, is presented using the Fourier transform, coupled to singular-value decomposition (SVD), and variability analyses including bootstrap. The results promote the utility of the STRF as a core functional descriptor of neurons in AI.
机译:光谱时域(STRF)为初级听觉皮层(AI)中的单个细胞提供了一种通用的,综合的,光谱的和时间的功能表征。在本文中,我们探讨了测量和分析STRF的不同方法的起源以及它们之间的关系。我们证明,使用频谱刺激时频变化的各种阵列(例如动态波纹,频谱时白噪声和时间正交涟漪组合(TORC))测量的STRF非常相似,证实了先前的发现,即STRF是细胞的稳健线性描述符。我们还提出了一个新的确定性分析框架,该框架采用傅立叶级数来描述刺激和响应中所包含的光谱时间调制。使用傅立叶变换,奇异值分解(SVD)以及包括自举在内的变异性分析,可以提供对STRF测量的更多见解,包括测量误差的性质和解释。结果促进了STRF作为AI中神经元的核心功能描述符的实用性。

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