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Model for Transition from Waves to Synchrony in the Olfactory Lobe of Limax

机译:Limax嗅叶中从波到同步转变的模型

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摘要

A biophysical model for the interactions between bursting (B) cells and nonbursting (NB) cells in the procerebral lobe of Limax is developed and tested. Phase-sensitivity of the NB cells is exhibited due to the strong inhibition from the rhythmically bursting B cells. Electrical and chemical junctions coupled with a parameter gradient lead to sustained periodic waves in the lobe. Excitatory interactions between the NB cells, which rarely fire, lead to stimulus evoked synchrony in the lobe oscillations. A novel calcium current is suggested to explain the effects of nitric oxide (NO) on the lobe. Gap junctions are shown both experimentally and through simulations to be required for the oscillating field potentials.
机译:建立并测试了Limax大脑前叶中爆发(B)细胞和非爆发(NB)细胞之间相互作用的生物物理模型。由于有节奏地爆发的B细胞具有强烈的抑制作用,因此显示了NB细胞的相敏性。电气和化学结点加上参数梯度会导致波瓣中持续的周期性波。很少触发的NB细胞之间的兴奋性相互作用会导致刺激引起叶振荡的同步性。建议使用新型钙电流来解释一氧化氮(NO)对肺叶的影响。实验中和通过仿真显示了振荡场电位所需的间隙结。

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