PCAM: a multi-user facility-based protein crystallization aparatus for microgravity

Daniel C. Carter; Brenda Wright; Teresa Miller

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PCAM: a multi-user facility-based protein crystallization aparatus for microgravity

机译：PCAM：用于微重力的基于多用户设施的蛋白质结晶区

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A facility-based protein crystllization apparatus for microgravity (PCAM) has been constructed and flown on a series of Space Shuttle Missions. The hardware development was undertaken largely because of the many important examples of quality improvements gained from crystal growth in the diffusion-limited environment in space. The concept was based on the adaptation for microgravity of a commonly available crystallization tray to increase sample density, to facilitate co-investigator participation and to improve flight logistics and handling.

机译：一种基于设施的微重力蛋白质结晶器（PCAM）已被建造并执行了一系列航天飞机飞行任务。进行硬件开发的主要原因是，在空间受限的扩散环境中晶体生长可带来许多质量改进的重要例子。该概念基于对常用结晶托盘的微重力进行调整，以增加样品密度，促进共同研究人员的参与并改善飞行后勤和处理。

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《Journal of Crystal Growth》 |1999年第4期|p.610-622|共13页
作者
Daniel C. Carter; Brenda Wright; Teresa Miller;
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);
原文格式 PDF
正文语种 eng
中图分类晶体学;
关键词
PCAM; Protein; Crystal; Microgravity; Vapor-diffusion; Shuttle;

机译：PCAM;蛋白;水晶;微重力蒸气扩散穿梭;

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专利

1. Crystallization of proteins under microgravity [J] . Betzel Christian, Duuml, vel Martina, FEBS Letters . 1989,第1期

机译：蛋白质在微重力下的结晶
2. Microgravity protein crystallization for drug development: a bold example of public sector entrepreneurship [J] . Scott Troy J., Vonortas Nicholas S. The journal of technology transfer . 2021,第5期

机译：药物开发的微匍匐蛋白结晶：公共部门企业家的大胆典范
3. Implementation of Temperature-Controlled Method of Protein Crystallization in Microgravity [J] . Strelov V. I., Zakharov B. G., Bezbakh I. Zh., Crystallography reports . 2018,第1期

机译：微再生中蛋白质结晶温度控制方法的实现
4. SURFACE (GLYCO-)PROTEINS: PRIMARY STRUCTURE AND CRYSTALLIZATION UNDER MICROGRAVITY CONDITIONS [C] . H. Claus, E. Akca, N. Schultz, European workshop on exo-/astro-biology . 2001

机译：表面（Glyco-）蛋白质：微匍匐条件下的初级结构和结晶
5. I. Crystallization of CRBPII mutants as a probe for understanding wavelength regulation. II. Reengineering and crystallization of Cellular Retinol Binding Protein II (CRBPII) as a fluorescent tag. III. Synthesis of gamma-carboxy glutamic acid and applications towards the synthesis of conantokins. [D] . Watson, Camille Theonie. 2016

机译：I.CRBPII突变体的结晶作为理解波长调节的探针。二。重新设计和结晶的细胞视黄醇结合蛋白II（CRBPII）作为荧光标记。三， γ-羧基谷氨酸的合成及其在刀豆蛋白合成中的应用。
6. Microgravity protein crystallization [O] . Alexander McPherson, Lawrence James DeLucas 2015

机译：微重力蛋白质结晶
7. PCAM: a multi-user facility-based protein crystallization apparatus for microgravity [O] . Carter, Daniel, Wright, Brenda, Miller, Teresa, 1999

机译：PCAM：基于多用户设备的微重力蛋白质结晶仪
8. Large scale crystallization of protein pharmaceuticals in microgravity via temperature change [R] . Long, Marianna M. 1992

机译：通过温度变化在微重力中大规模结晶蛋白质药物

PCAM: a multi-user facility-based protein crystallization aparatus for microgravity

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