Efficacy of Panax ginseng extract combined with cephalexin as a dry cow therapy

Camila Beccaria; Celina Baravalle; Paula Silvestrini; Maria S. Renna; Ana I. Molineri; Marcelo L. Signorini; Veronica E. Neder; Guillermo A. Suarez Archilla; Luis F. Calvinho; Bibiana E. Dallard

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Efficacy of Panax ginseng extract combined with cephalexin as a dry cow therapy

机译：Panax人参提取物联合头孢氨苄作为干牛治疗的疗效

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Our objective was to evaluate the efficacy of intramammary administration, at drying-off, of a Panax ginseng extract (PGe) combined with cephalexin (Ceph) on the post-calving bacterio-logical cure rate of pre-existing intramammary infections (IMI) and on the occurrence of new IMI during the dry period. In addition, milk yield and somatic cell count (SCC) in the post-treatment lactation were evaluated. One hundred and eight late-lactation cows were randomly divided into two experimental groups and were treated at drying-off with Ceph alone or PGe combined with Ceph.Cure rates for IMI present at drying-off were similar for both treatments (OR = 0.95, 95% CI = 0.33-2.74). Cure rates for Staphylococcus aureus were lower (OR = 15.4, 95% CI = 1.66-142.52) in quarters treated with PGe + Ceph than in those treated with Ceph alone. Intramammary infusion of PGe + Ceph at drying-off had no effect on preventing new dry period IMI (OR = 0.75, 95% CI = 0.38-1.51), compared with infusion of Ceph alone. Milk production and SCC in the ensuing lactation were not affected by PGe + Ceph treatment. In conclusion, addition of PGe to dry cow therapy did not show any advantage over the use of dry cow therapy alone.

机译：我们的目的是评估脑内局部给药的疗效，干燥，掉合金提取物（PGE）与头孢氨苄（CEPH）联合在含有预计的床罩感染（IMI）和干燥期间新IMI的发生。此外，评价后治疗后哺乳期的牛奶产量和体细胞计数（SCC）。一百八奶牛随机分为两组实验组，用Ceph脱掉两种实验组，或者用Ceph与Ceph.Cefule，在干燥时的IMI的速率相似（或= 0.95， 95％CI = 0.33-2.74））。用PGE + Ceph处理的宿舍，金黄色葡萄球菌的固化率较低（或= 15.4,95％CI = 1.66-142.52），其仅在用Ceph处理的那些。与单独输注Ceph的输注相比，在干燥时，在干燥时，在干燥时输注PGE + CEPH的含量没有影响。随后的哺乳期牛奶生产和SCC不受PGE + Ceph治疗的影响。总之，加入干牛治疗的PGE并未对单独使用干牛疗法显示任何优势。

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来源
《Journal of dairy research》 |2021年第1期|64-68|共5页
作者
Camila Beccaria; Celina Baravalle; Paula Silvestrini; Maria S. Renna; Ana I. Molineri; Marcelo L. Signorini; Veronica E. Neder; Guillermo A. Suarez Archilla; Luis F. Calvinho; Bibiana E. Dallard;
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作者单位

Laboratorio de Biologia Celular y Molecular Aplicada Instituto de Ciencias Veterinarias del Literal (ICIVET-Litoral) Universidad Nacional del Literal (UNL)/Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET) Esperanza Santa Fe Argentina Facultad de Ciencias Veterinarias (UNL) Esperanza Santa Fe Argentina;

Laboratorio de Biologia Celular y Molecular Aplicada Instituto de Ciencias Veterinarias del Literal (ICIVET-Litoral) Universidad Nacional del Literal (UNL)/Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET) Esperanza Santa Fe Argentina Facultad de Ciencias Veterinarias (UNL) Esperanza Santa Fe Argentina;

Laboratorio de Biologia Celular y Molecular Aplicada Instituto de Ciencias Veterinarias del Literal (ICIVET-Litoral) Universidad Nacional del Literal (UNL)/Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET) Esperanza Santa Fe Argentina Facultad de Ciencias Veterinarias (UNL) Esperanza Santa Fe Argentina;

Laboratorio de Biologia Celular y Molecular Aplicada Instituto de Ciencias Veterinarias del Literal (ICIVET-Litoral) Universidad Nacional del Literal (UNL)/Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET) Esperanza Santa Fe Argentina Facultad de Ciencias Veterinarias (UNL) Esperanza Santa Fe Argentina;

lnstituto de Investigacion de la Cadena Lactea (IdlCaL) Instituto Nacional de Tecnologia Agropecuaria (INTA) -CONICET Rafaela Santa Fe Argentina;

Facultad de Ciencias Veterinarias (UNL) Esperanza Santa Fe Argentina lnstituto de Investigacion de la Cadena Lactea (IdlCaL) Instituto Nacional de Tecnologia Agropecuaria (INTA) -CONICET Rafaela Santa Fe Argentina;

lnstituto de Investigacion de la Cadena Lactea (IdlCaL) Instituto Nacional de Tecnologia Agropecuaria (INTA) -CONICET Rafaela Santa Fe Argentina;

lnstituto de Investigacion de la Cadena Lactea (IdlCaL) Instituto Nacional de Tecnologia Agropecuaria (INTA) -CONICET Rafaela Santa Fe Argentina;

Facultad de Ciencias Veterinarias (UNL) Esperanza Santa Fe Argentina lnstituto de Investigacion de la Cadena Lactea (IdlCaL) Instituto Nacional de Tecnologia Agropecuaria (INTA) -CONICET Rafaela Santa Fe Argentina;

Laboratorio de Biologia Celular y Molecular Aplicada Instituto de Ciencias Veterinarias del Literal (ICIVET-Litoral) Universidad Nacional del Literal (UNL)/Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET) Esperanza Santa Fe Argentina Facultad de Ciencias Veterinarias (UNL) Esperanza Santa Fe Argentina;

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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类
关键词
Cephalexin; dry cow therapy; efficacy; intramammary infections; Panax ginseng;

机译：头孢氨苄;干牛疗法;功效;内部感染;Panax Ginseng.;

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Efficacy of Panax ginseng extract combined with cephalexin as a dry cow therapy

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