首页> 外文期刊>Journal of dairy research >The importance of being earnest with mastitis research
【24h】

The importance of being earnest with mastitis research

机译:患乳腺炎的重点是乳腺炎研究

获取原文
获取原文并翻译 | 示例
           

摘要

To the Editor A recent Research Reflection raised the issue of the relevance of a sizeable part of the current research on mastitis (Hillerton, 2020). The main criticism is that the surge of molecular, DNA-based technologies and in silico research tools occurred at the expense of animal experi-mentation. I concur with this view and would add a few comments. In the last decade, 'omics' studies have been flooding the mastitis research field. There would be nothing wrong with this if these studies were followed or accompanied by experi-mental testing of the hypotheses generated. Initial explorations made possible by technological breakthroughs generate databases that can be mined thanks to powerful bioinformatics. These techniques are sensible means of opening-up new avenues of research. It has been convin-cingly argued that data-driven science and hypothesis-driven science are complementary and best carried out iteratively (Kell and Oliver, 2004). Proponents of DNA-based techniques point out that one of the strengths of their approach is that there is no initial hypothesis that could serve as blinders for research: no input, high throughput... but, all too often, no output (Friedberg, 2008). In any case, interpretations of their results are no evidence, to acquire this quality they need experimental testing.
机译:对编辑最近的研究反思提出了关于乳腺炎目前关于乳腺炎(Hillerton,2020)的大量研究的相关性的问题。主要批评是,分子,基于DNA的技术和Silico研究工具的浪涌发生在牺牲动物实验中。我同意这个观点,会增加一些评论。在过去的十年中,'OMICS'的研究一直在淹没乳腺炎研究领域。如果遵循这些研究或伴随着产生的假设的实验测试,就会出错。通过技术突破实现的初始探索可以通过强大的生物信息学,生成可以开采的数据库。这些技术是开放新途径的明智的方法。它一直致力于召集数据驱动的科学和假设驱动科学是互补的,最好的迭代(Kell和Oliver,2004)。基于DNA的技术的支持者指出,他们的方法的一个优势是没有初步假设,可以作为研究的盲目:没有输入,高吞吐量......但是,频繁,没有输出(Friedberg, 2008)。无论如何,对结果的解释是没有证据,以获得他们需要实验测试的这种质量。

著录项

  • 来源
    《Journal of dairy research》 |2021年第1期|117-118|共2页
  • 作者

    Pascal Rainard;

  • 作者单位

    INRAE Universite de Tours UMR ISP F-37380 Nouzilly France;

  • 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号