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首页> 外文期刊>Journal of dairy research >Milk metabolites, proteins and oxidative stress markers in dairy cows suffering from Staphylococcus oureus subclinical mastitis with or without spontaneous cure
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Milk metabolites, proteins and oxidative stress markers in dairy cows suffering from Staphylococcus oureus subclinical mastitis with or without spontaneous cure

机译：牛奶代谢物，蛋白质和氧化胁迫标志物在牛奶奶牛患有葡萄球菌患者亚洲亚临床乳腺炎，没有自发治愈

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Our objective was to evaluate relationships between milk components (acute phase proteins, enzymes, metabolic parameters and oxidative indices) and the spontaneous cure outcome of Staphylococcus aureus subclinical mastitis in dairy cows. The values of haptoglobin, serum amyloid A (SAA), malondialdehyde (MDA), total antioxidant capacity, milk urea nitrogen (MUN), lactate dehydrogenase (LDH), alkaline phosphatase (ALP), electrolytes (Cl and K), total protein, albumin, α-lactalbumin, β-lactoglobulin, and immunoglobulin were measured in milk samples of S. aureus subclinical mastitis cows with spontaneous cure (n = 23), S. aureus subclinical mastitis cows without spontaneous cure (n = 29) and healthy cows (n = 23). The comparison of measured parameters revealed that subclinical mastitis cows with spontaneous cure had lower ALP and haptoglobin concentrations both at diagnosis and after cure (P ＜ 0.05). In contrast, total antioxidant capacity and MDA concentration in subclinical mastitis cows without spontaneous cure significantly increased with time (P ＜ 0.05). We can suggest that elevated haptoglobin concentration and higher ALP activity indicative of enhanced oxidative stress could potentially serve as early diagnostic indicators of chronic disease and the persistence of S. aureus subclinical mastitis in dairy cows.
机译：我们的目的是评估乳成分（急性期蛋白，酶，代谢参数和氧化指数）的关系以及奶牛金黄色葡萄球菌的自发治疗结果。 Haptoglobin，血清淀粉样蛋白A（SAA），丙二醛（MDA），总抗氧化能力，乳尿素氮（MUN），乳酸脱氢酶（LDH），碱性磷酸酶（ALP），电解质（CL和K），总蛋白，在具有自发固化的金黄色葡萄球菌亚临床乳腺炎牛的牛奶样品中测量白蛋白的牛奶样品中的白蛋白，S. aureus亚临床乳腺炎牛的牛奶样品（n = 29）和健康奶牛（n = 23）。测量参数的比较表明，具有自发固化的亚临床乳腺炎牛在诊断和固化后的ALP和HaptoGlobin浓度下降（P <0.05）。相比之下，无自发固化的亚临床乳腺炎牛的总抗氧化能力和MDA浓度随时间显着增加（P <0.05）。我们可以表明，升高的哈达福蛋白浓度和较高的ALP活性表明具有增强的氧化应激可能是慢性疾病的早期诊断指标和奶牛在奶牛的金黄色葡萄球菌亚临床乳腺炎的持续性。

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