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首页> 外文期刊>Journal of dairy research >Use of partial budgeting to determine the economic benefits of antibiotic treatment of chronic subclinical mastitis caused by Streptococcus uberis or Streptococcus dysgalactiae.
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Use of partial budgeting to determine the economic benefits of antibiotic treatment of chronic subclinical mastitis caused by Streptococcus uberis or Streptococcus dysgalactiae.

机译：使用部分预算来确定抗生素治疗由乳房链球菌或痢疾链球菌引起的慢性亚临床乳腺炎的经济效益。

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The economic effect of lactational antibiotic treatment of chronic subclinical intramammary infections due to Streptococcus uberis or Streptococcus dysgalactiae was explored by means of partial budgeting. Effects at cow level and herd level were modelled, including prevention of clinical mastitis episodes and the prevention of transmission of infections. Input variables for our deterministic model were derived from literature or based on 2002/2003 dairy prices and farming conditions in The Netherlands. Sensitivity analysis was used to examine the effect of uncertainty around input variables or changes in price estimates. On farms where pathogen transmission was prevented through proper udder health management, 3-d antibiotic treatment during lactation resulted in an average net profit of Euro+11.62 over no treatment while 8-d antibiotic treatment had an average negative net result of Euro-21.83. Sensitivity analysis showed that profitability depends on the probability of treatment-induced cure, pathogen transmission rates, culling rate, retention pay-off, and costs of antibiotic treatment. Three-day antibiotic treatment of chronic subclinical streptococcal mastitis is economically profitable over a range of input values for cure probabilities, transmission rates and losses due to culling. In contrast, 8-d lactational treatment is only profitable for very valuable animals, on farms where the risk of pathogen transmission is high and/or when the farmer is likely to cull a high percentage of cows with subclinical mastitis. Because bacterial flora, cow characteristics and management differ widely between farms, the economic outcome of lactational treatment of chronic subclinical streptococcal mastitis may be highly farm-dependent.
机译：通过部分预算研究了哺乳类抗生素治疗因乳房链球菌或痢疾链球菌引起的慢性亚临床乳房内感染的经济效果。对奶牛和畜群水平的影响进行了建模，包括预防临床乳腺炎发作和预防感染传播。我们确定性模型的输入变量来自文献或基于2002/2003年度荷兰乳制品价格和养殖条件。敏感性分析用于检查不确定性对输入变量或价格估计值变化的影响。在通过适当的乳房健康管理防止病原体传播的农场中，泌乳期间进行3-d抗生素治疗的平均净利润为Euro + 1.62，而未进行处理的平均净利润为Euro-21.83，而未进行处理的平均净利润为Euro-21.83。敏感性分析表明，获利能力取决于治疗诱导治愈的可能性，病原体传播率，剔除率，保留收益和抗生素治疗成本。在治愈概率，传播速率和剔除造成的损失等一系列输入值范围内，对慢性亚临床链球菌性乳腺炎进行三天抗生素治疗在经济上是有利可图的。相反，只有在非常有价值的动物，病原体传播风险很高的农场和/或农民可能淘汰高百分比的患有亚临床乳腺炎的母牛时，8d泌乳治疗才有利可图。由于不同农场之间的细菌菌群，母牛的特征和管理方式存在很大差异，因此对慢性亚临床链球菌性乳腺炎进行泌乳治疗的经济结果可能高度依赖农场。

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