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Effect of Dose Reduction on the Ability of Digital Mammography to Detect Simulated Microcalcifications

机译:减少剂量对数字化乳腺X线摄影检测模拟微钙化能力的影响

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The purpose of this article was to report the relationship between radiation dose and the ability of sentence digital mammography to detect microcalcifications. All images were acquired by computed radiography and an anthropomorphic breast phantom. The tube voltage and anode/filter combination used were 28 kVp and Mo/Mo. Simulated microcalcifications with an approximate diameter of 250–350 μm were positioned on the phantom. Groups of six microcalcifications were arranged in one of two patterns, a line cluster 1 cm long or a hexagonal cluster 4 mm wide. One of the six microcalcifications was removed to create a negative control. Each cluster was placed on 25 different points. Four levels of milliampere-second (mAs) values were applied: 100%, 50%, 25%, and 12.5%. Five staff radiologists participated in an observer performance test. All observers used a workstation with a 3-megapixel monochrome LCD monitor. The areas under the receiver-operating characteristics curves (AUC) were used to compare diagnostic performance among the four doses. The overall AUC scores were 0.97 with 100% mAs, 0.93 (n.s.) with 50%, 0.90 (p < 0.05) with 25%, and 0.81 (p < 0.01) with 12.5% mAs. Among the negative series, the percentage of images on which observers were able to identify the removed microcalcification point decreased from 88.8% with 100% mAs to 83.6% (n.s.) with 50%, 74.8% (p < 0.001) with 25%, and 67.2% (p < 0.001) with 12.5% mAs. A certain level of dose reduction in digital mammography may be an option.
机译:本文的目的是报告辐射剂量与句子数字化乳腺X线摄影检测微钙化的能力之间的关系。所有图像均通过计算机射线照相和拟人化的乳房幻像获得。所用的管电压和阳极/滤波器组合为28 kVp和Mo / Mo。直径约250-350μm的模拟微钙化物位于模型上。六个微钙化的组以以下两种模式之一排列:长1 cm的线簇或宽4 mm的六边形簇。除去六个微钙化之一,以产生阴性对照。每个群集放置在25个不同的点上。应用了四个级别的毫安秒(mAs)值:100%,50%,25%和12.5%。五名放射线职员参加了观察员性能测试。所有观察员都使用带有3兆像素单色LCD监视器的工作站。接收器工作特性曲线(AUC)下的面积用于比较四种剂量之间的诊断性能。总体AUC评分在100%mAs时为0.97,在50%时为0.93(n.s.),在25%时为0.90(p <0.05),在12.5%mAs下为0.81(p <0.01)。在负系列中,观察者能够识别出已去除微钙化点的图像百分比从100%mAs的88.8%降至50%的83.6%(ns),25%的74.8%(p <0.001)和67.2%(p <0.001)和12.5%mAs。数字化乳腺摄影术中一定程度的剂量减少可能是一种选择。

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