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首页> 外文期刊>Journal of ecotoxicology & environmental monitoring >EVALUATION OF ANTIBACTERIAL ACTIVITY USING CRUDE EXTRACTS OF AZADIRACHTA INDICA
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EVALUATION OF ANTIBACTERIAL ACTIVITY USING CRUDE EXTRACTS OF AZADIRACHTA INDICA

机译：用印度叠氮粗提取物评估抗菌活性

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摘要

To determine antibacterial activity of Azadirachta indica, crude extracts from different parts of A. indica were tested against bacterial strains of clinical significance. Extraction of bio-active principles in appropriate solvent was followed by evaluation of antibacterial activity by disc diffusion assay against selected bacterial stains. The pattern of inhibition largely depends upon extraction procedure, plant part, physiological and morphological state of plant, extraction solvent and microorganisma tested. Of different plant materials tested, extracts prepared from leaves showed significantly higher efficacy. Extracts prepared using organic solvents significantly higher efficacy than their corresponding aqueous extracts. However, no activity was observed in the aqueous extracts. Among the extracts that were significantly active, extract obtained using ethanol showed significantly higher efficacy against bacterial strains tested. Gram negative stains were more sensitive than Gram positive bacteria. The antibacterial activities were found to be dose dependent.
机译：为了确定印za的抗菌活性，对印from不同部位的粗提物进行了针对具有临床意义的细菌菌株的测试。在适当溶剂中提取生物活性成分，然后通过针对所选细菌污渍的椎间盘扩散试验评估抗菌活性。抑制方式主要取决于提取程序，植物部位，植物的生理和形态状态，提取溶剂和所测试的微生物。在测试的不同植物材料中，从叶中提取的提取物显示出明显更高的功效。使用有机溶剂制备的提取物的功效明显高于其相应的水性提取物。然而，在水提取物中未观察到活性。在具有显着活性的提取物中，使用乙醇获得的提取物对测试的细菌菌株显示出明显更高的功效。革兰氏阴性菌比革兰氏阳性菌更敏感。发现抗菌活性是剂量依赖性的。

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