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首页> 外文期刊>Journal of Environmental Management >Prioritization of pharmaceuticals in water environment in China based on environmental criteria and risk analysis of top-priority pharmaceuticals
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Prioritization of pharmaceuticals in water environment in China based on environmental criteria and risk analysis of top-priority pharmaceuticals

机译：基于环境标准和高优先级药物风险分析的中国水环境中药物优先级

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Numerous studies have shown that a wide range of pharmaceuticals are present in the environment and many of their adverse biological effects on the aquatic ecosystem and human health are unknown. Due to the high population density and large number of pharmaceuticals produced and consumed in China, a systematic approach is needed to identify pharmaceuticals that require greater attention. The present study provides a ranking of pharmaceuticals in China in terms of their occurrence (O), persistence, bioaccumulation, and toxicity (PBT) based on the predicted environmental concentration (PEC). The total and partial ranking method implemented in the decision analysis by ranking techniques (DART) tool was used, which is an easy-to-use tool for the analysis of datasets. Using the DART approach, 10 pharmaceuticals were selected as priority compounds. These pharmaceuticals included antibiotics, anti-inflammatory and antilipidemic. In order to identify the characteristics of the priority pharmaceuticals, ecotoxicological endpoints were considered. The results of this study and the priority list facilitate the selection of candidate pollutants in future monitoring studies.
机译：大量研究表明，环境中存在着各种各样的药物，并且它们对水生生态系统和人类健康的许多不利生物学影响尚不清楚。由于中国人口密度高，生产和消费的药品数量众多，因此需要一种系统的方法来确定需要更多关注的药品。本研究基于预测的环境浓度（PEC），根据其发生率（O），持久性，生物蓄积性和毒性（PBT）对中国的药物进行了排名。使用了通过排名技术（DART）工具在决策分析中实施的全部和部分排名方法，这是一种易于使用的数据集分析工具。使用DART方法，选择了10种药物作为优先化合物。这些药物包括抗生素，抗炎药和抗血脂药。为了确定优先药物的特征，考虑了生态毒理学终点。这项研究的结果和优先级列表有助于在将来的监测研究中选择候选污染物。

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