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首页> 外文期刊>Journal of environmental science and health >Controlled-release of fluazinam from biodegradable PLGA-based microspheres
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Controlled-release of fluazinam from biodegradable PLGA-based microspheres

机译:来自生物降解的PLGA基微球的氟化蛋白酶的控制释放

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摘要

Pesticides are biological or chemical substances used to manage pests and diseases. Encapsulation of pesticides in biodegradable carriers creates a slow-release system that can improve water dispersibility and prolong residual activity. We prepared two kinds of poly (lactic-co-glycolic acid)(PLGA) nanoparticles (NPs) with polyvinyl alcohol (PVA) and sodium dodecyl sulfate (SDS) surfactants. These were used to encapsulate the fungicide fluazinam (Flu) against Rhizoctonia solani using the Shirasu Porous Glass (SPG) membrane emulsification method. Both nanoparticles had uniform spherical shapes with average diameters of 314.13 nm (SDS) and 612.80 nm (PVA). The slow-release microspheres had excellent sustained-release properties, resistance to UV degradation, storage stability, leaf surface coverage and antifungal efficacy compared to the commercial formulation.
机译:农药是用于管理害虫和疾病的生物或化学物质。生物降解载体中农药的封装产生了一种缓慢释放系统,可以改善水分散性和延长残留活性。我们制备了两种聚乙烯醇(PVA)和十二烷基硫酸钠(SDS)表面​​活性剂的两种聚(乳酸二乙醇酸)(PLGA)纳米颗粒(NPS)。这些用于使用Shirasu多孔玻璃(SPG)膜乳化方法将杀菌剂Fluazinam(流感)粘合抗毒藻酰苯胺。两个纳米颗粒都具有均匀的球形形状,平均直径为314.13nm(SDS)和612.80nm(PVA)。与商业制剂相比,慢释放微球具有优异的缓释性能,抗紫外降解,储存稳定性,叶片表面覆盖和抗真菌效果。

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