...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Food Science >Czech Ethanol-Free Propolis Extract Displays Inhibitory Activity against a Broad Spectrum of Bacterial and Fungal Pathogens
【24h】

Czech Ethanol-Free Propolis Extract Displays Inhibitory Activity against a Broad Spectrum of Bacterial and Fungal Pathogens

机译：捷克无乙醇蜂胶提取物对多种细菌和真菌病原体均显示抑制活性

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Propolis acts primarily as a biocide against invasive bacteria and fungi in the hive, suggesting its potential for industrial applications. In food application, propolis is considered as a chemical preservative in meat products, extending shelf life of frozen meat and other food. The mechanism of action is still unclear due to the synergy of multiple compounds contained in propolis and due to parallel targeting of multiple pathways within each affected organism. Here, we examined the antimicrobial properties of dimethylsulfoxide (DMSO) Czech propolis extract. Until recently, DMSO was only rarely used in the propolis studies, although the other solvents tested (mostly ethanol) may significantly affect the observed inhibitory effects, notwithstanding the antimicrobial effects of ethanol itself. Here, we provide results of zone inhibition tests against Aspergillus fumigatus, Microsporum gypseum, Microsporum canis, Candida albicans, Escherichia coli, Staphylococcus aureus, Listeria monocytogenes, and Enterococcus faecalis. Although we determined inhibitory effects against all the microorganisms tested, the dose-dependent response curves were not similar to each other. While inhibitory effects against C. albicans or 5. aureus were strictly dose-dependent, responses of M. gypseum and E. faecalis displayed plateau across the broad range of concentrations tested. Interestingly, response of E. coli revealed the double-peak dose-dependent curve, and responses of M. canis and L. monocytogenes decreased at the highest concentrations tested. Suggested is evaluation of DMSO propolis extracts in experimental treatment of human and veterinary infections, preferably in multitherapy with antibiotics.
机译：蜂胶主要起蜂巢中侵袭性细菌和真菌的杀菌作用，表明其在工业上的潜力。在食品应用中，蜂胶被认为是肉制品中的化学防腐剂，可延长冷冻肉和其他食品的保质期。由于蜂胶中所含多种化合物的协同作用以及由于每种受影响生物体内多种途径的平行靶向，其作用机理仍不清楚。在这里，我们检查了二甲基亚砜（DMSO）捷克蜂胶提取物的抗菌性能。直到最近，尽管测试的其他溶剂（主要是乙醇）可能会显着影响所观察到的抑制作用，但尽管乙醇本身具有抗菌作用，但在蜂胶研究中很少使用DMSO。在这里，我们提供了针对烟曲霉，石膏小孢子菌，犬小孢子菌，白色念珠菌，大肠杆菌，金黄色葡萄球菌，单核细胞增生李斯特菌和粪肠球菌的区域抑制测试结果。尽管我们确定了对所有测试微生物的抑制作用，但剂量依赖性反应曲线彼此并不相似。尽管对白色念珠菌或5.金黄色葡萄球菌的抑制作用严格依赖于剂量，但在广泛测试的浓度范围内，埃及支原体和粪肠球菌的反应均表现出平台性。有趣的是，在最高测试浓度下，大肠杆菌的反应显示出双峰剂量依赖性曲线，犬支原体和单核细胞增生李斯特菌的反应下降。建议评估DMSO蜂胶提取物在人和兽医感染的实验治疗中的效果，最好是在抗生素的多药治疗中。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号