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首页> 外文期刊>Journal of Food Science >The Biomimetic Immunoassay Based on Molecularly Imprinted Polymer: A Comprehensive Review of Recent Progress and Future Prospects
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The Biomimetic Immunoassay Based on Molecularly Imprinted Polymer: A Comprehensive Review of Recent Progress and Future Prospects

机译：基于分子印迹聚合物的仿生免疫测定：近期进展和未来展望的综述

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摘要

Immunoassay, based on a selective affinity of the biological antibody for its antigen, is one of the most usual analytical methods in food safety and environmental chemistry. However, it presents several drawbacks because of the nature of the antibody. Molecular imprinting technique, due to its high selectivity and stability, ease of preparation and low cost, has shown great potential in producing artificial antibodies in biomimetic immunoassays. This article focuses on the recent states, advantages, current problems and outlooks of molecularly imprinted radio, fluoro, enzyme-linked and chemiluminescent immunoassays, and biomimetic immunosensor, with special emphasis on the challenges in developing biomimetic enzyme-linked immunosorbent assays (BELISAs). The biomimetic immunoassay method will provide an important new analysis platform in food safety, although the sensitivity and specificity is relatively low.
机译：基于生物抗体对其抗原的选择性亲和力的免疫测定法是食品安全和环境化学中最常用的分析方法之一。然而，由于抗体的性质，它存在几个缺点。分子印迹技术因其高选择性和稳定性，易于制备和低成本而在仿生免疫测定中显示出产生人工抗体的巨大潜力。本文着重介绍分子印迹放射，荧光，酶联和化学发光免疫测定以及仿生免疫传感器的最新状态，优势，当前问题和前景，特别着重于开发仿生酶联免疫吸附测定（BELISA）的挑战。尽管敏感性和特异性相对较低，但仿生免疫分析方法仍将为食品安全提供重要的新分析平台。

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  • 来源
    《Journal of Food Science》 |2011年第2期|p.R69-R75|共7页
  • 作者

    Z.X. Xu; H.J. Gao; LM. Zhang; X.Q. Chen; X.C. Qiao;

  • 作者单位

    College of Food Science and Engineering, Shandong Agricultural Univ., Taian 271018, China;

    College of Forestry, Shandong Agricultural Univ., Taian 271018, China;

    College of Food Science and Engineering, Shandong Agricultural Univ., Taian 271018, China;

    College of Food Science and Engineering, Shandong Agricultural Univ., Taian 271018, China;

    College of Food Science and Engineering, Shandong Agricultural Univ., Taian 271018, China;

  • 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    application; artificial antibody; biomimetic immunoassay; molecular imprinting;

    机译：应用;人工抗体仿生免疫测定分子印迹;

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