...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Hazardous Materials >Effects of 2,4-dinitrotoluene exposure on enzyme activity, energy reserves and condition factors in common carp (Cyprinus carpio)
【24h】

Effects of 2,4-dinitrotoluene exposure on enzyme activity, energy reserves and condition factors in common carp (Cyprinus carpio)

机译：2,4-二硝基甲苯暴露对鲤鱼酶活性，能量储备和条件因子的影响

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

In this study relative condition factor (RCF) and hepatosomatic index (HSI) as well as the available energy reserves of common carp (Cyprinus carpio) by 2,4-DNT semi-static bioassay were determined and linked to effects of enzymes in liver tissues. Fish were exposed at sublethal concentrations of 2,4-DNT (0.13 μg/L, 0.1, 0.5, 1.0mg/L) for 7 and 15d. Based on the results, there was no significant change in all parameters measured in fish exposed to 2,4-DNT at environmental related concentration, but 2,4-DNT stress in fish exposed to higher concentrations reflected the significant changes of physiological and biochemical responses. 2,4-DNT stress resulted in EROD activity induction in the liver, and the levels of EROD activity ranged from 0.39- to 1.83-fold higher than control. For GK, Na~+/K~+-ATPase, and GST, these enzyme activity continued to decline after exposure to 0.1, 0.5 and l.0mg/L 2,4-DNT, whereas the trend on GK and Na~+/K~+-ATPase was more obvious than GST. Through principal component analysis, effects by 2,4-DNT-stress in each test group were distinguished. Additionally, indications of a trade-off between metabolic cost of toxicant exposure and processes vital to the survival of the organism were seen at the enzyme activity level as well as on higher levels of biological organization.
机译：在这项研究中，确定了相对条件因子（RCF）和肝体指数（HSI）以及通过2,4-DNT半静态生物测定法确定的鲤鱼（Cyprinus carpio）的可用能量储备，并将其与肝组织中酶的作用相关联。鱼在2,4-DNT（0.13μg/ L，0.1，0.5，1.0mg / L）的致死浓度下暴露7天和15天。根据结果​​，暴露于环境相关浓度的2,4-DNT的鱼的所有参数均无显着变化，但是暴露于较高浓度的鱼的2,4-DNT压力反映了生理和生化反应的显着变化。 2,4-DNT应激导致肝脏中EROD活性的诱导，并且EROD活性水平比对照组高0.39-1.83倍。对于GK，Na〜+ / K〜+ -ATPase和GST，这些酶的活性在暴露于0.1、0.5和1.0mg / L的2,4-DNT后继续下降，而GK和Na〜+ / K〜+ -ATPase比GST更明显。通过主成分分析，区分了每个测试组在2,4-DNT胁迫下的效果。另外，在酶活性水平以及更高水平的生物组织上，都可以看到毒物暴露的代谢成本和对生物生存至关重要的过程之间的权衡取舍。

著录项

  • 来源
    《Journal of Hazardous Materials》 |2012年第2012期|p.299-307|共9页
  • 作者

    Jingbo Xu; Nan Jing;

  • 作者单位

    Department of Environmental Science and Engineering, Northeast Normal University, Changchun 130024, China,Key Laboratory for Wetland Ecology and Vegetation Restoration of National Environmental Protection, Northeast Normal University, Changchun 130024, China;

    Department of Logistics Engineering South China University of Technology, Guangzhou 510641, China;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    2,4-DNT; common carp; enzyme activity; energy reserves; metabolic cost;

    机译：2,4-DNT;鲤鱼酶活性能源储备;代谢成本;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号