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Revisiting United States valuation of EQ-5D states

机译:重新评估EQ-5D国家在美国的估值

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摘要

In the original US valuation study of EQ-5D states, all worse-than-dead time trade-off responses (26% of the sample) were divided by 39 to increase the QALY estimates. This transformation has no theoretical justification and motivates this re-examination. Using the publically available dataset, we compared three alternative random utility models: instant (IRUM), angular (ARUM), and episodic (ERUM) models. Each leads to a distinct econometric estimator: mean ratio, ratio of means, and coefficient, respectively. IRUM suggests that 203 of the 243 EQ-5D states are worse-than-dead, which has little face validity compared to ARUM and ERUM (42 and 3 WTD states). ARUM and ERUM estimates are proportionally related such that losses in QALYs are approximately 37% larger under ARUM than ERUM. Compared to ERUM, economic evaluations using ARUM estimates emphasize quality of life, and this difference may influence policy decisions. Either ERUM or ARUM values sets are recommended over the original, transformed set.
机译:在美国最初对EQ-5D州进行的估值研究中,所有差于死时间的权衡响应(占样本的26%)均除以39,以提高QALY估计值。这种转变没有理论上的依据,并激发了这种重新审视。使用公开可用的数据集,我们比较了三种替代的随机效用模型:即时(IRUM),角度(ARUM)和情节(ERUM)模型。每一个都导致一个不同的计量经济学估计量:分别为平均比率,均值比率和系数。 IRUM表明,在243个EQ-5D状态中,有203个状态不如死,与ARUM和ERUM(42个和3个WTD状态)相比,其面部有效性很小。 ARUM和ERUM估计值成比例地相关,因此在ARUM下QALY的损失比ERUM大约37%。与ERUM相比,使用ARUM估计进行的经济评估强调生活质量,这种差异可能会影响政策决策。建议在原始转换集上使用ERUM或ARUM值集。

著录项

  • 来源
    《Journal of health economics》 |2011年第5期|p.1057-1063|共7页
  • 作者单位

    Health Outcomes & Behavior Program, Moffltt Cancer Center, 12902 Magnolia Drive, MRC-CANCONT, Tampa, FL 33612-9416, United States,Department of Economics, University of South Florida, United States;

    Department of Medical Psychology and Psychotherapy, Erasmus MC, PO Box 2040 3000 CA Rotterdam, The Netherlands,Viersprong Institute for studies on Personality Disorders VISPD, The Netherlands;

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  • 正文语种 eng
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  • 关键词

    qaly time trade-off health-related quality of life;

    机译:与健康相关的生活质量的时间权衡;

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