...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal oflaser Applications >Laser flash photolysis of diazo-2. a caged calcium chelator: The relationship between the extent and rate of smooth muscle relaxation
【24h】

Laser flash photolysis of diazo-2. a caged calcium chelator: The relationship between the extent and rate of smooth muscle relaxation

机译：重氮2的激光闪光光解。关在笼中的钙螯合剂：平滑肌松弛程度和速率之间的关系

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Relaxations brought about by laser flash photolysis of diazo-2, a caged calcium chelator, were recorded in the anterior byssus retractor muscle (ABRM) of Mytilus edulis (a molluscan "catch" muscle). The relaxation rate was characterized by half-time (T_(1/2)) and one-h'fth-time (T_(1/5)). We show that, unlike, e.g., in the mammalian cardiac muscle, the relaxation rate increases with the extent of relaxation (the latter being expressed as a percentage of an immediately preceding activation by Ca~(2+)), in a manner similar to the Ca~(2+) activation process, as shown in other muscles [Lea and Ashley. J. Physiol. (Lond.) 427, 435-453 (1990): Saeki et al., J. Mol. Cell. Cardiol. 36. 371-380 (2004)]. This increase (i.e., decrease in T_(1/2) and T_(1/5)) levels off at extent of relaxation approx= 50%. The present paper highlights the need to take inlo account the differences in the extent of smooth muscle (especially the catch or "latch" type) relaxation. The data may be used in modeling the mechanism underlying the calcium-dependent (phasic) smooth muscle relaxations.
机译：笼养的钙螯合剂重氮2的激光闪光光解引起的松弛被记录在可食性Mytilus的前屈肌牵开肌（ABRM）（软体动物的“捕获”肌肉）中。弛豫率的特征在于一半的时间（T_（1/2））和八分之一的时间（T_（1/5））。我们显示出，与例如在哺乳动物心肌中不同，松弛速率随松弛程度的增加而增加（后者表示为Ca〜（2+）紧接在其之前激活的百分比），其方式类似于Ca〜（2+）激活过程，如其他肌肉所示[Lea和Ashley。 J.生理学。 （Lond。）427，435-453（1990）：Saeki等，J.Mol.Biol.215：403-10。细胞。乙二醇。 36. 371-380（2004）]。这种增加（即，T_（1/2）和T_（1/5）的减少）在松弛程度约为50％时趋于平稳。本文强调需要单独考虑平滑肌放松程度的差异（尤其是抓地力或“闩锁”类型）。该数据可用于对钙依赖性（阶段性）平滑肌松弛基础的机制进行建模。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号