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首页> 外文期刊>Journal of Materials Research >Synthesis and characterization of multiphase bioactive glass-ceramics in the CaO-MgO-SiO_2 system with B_2O_3 additive
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Synthesis and characterization of multiphase bioactive glass-ceramics in the CaO-MgO-SiO_2 system with B_2O_3 additive

机译：含B_2O_3的CaO-MgO-SiO_2体系中多相生物活性玻璃陶瓷的合成与表征

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摘要

A glass-ceramic (GCO) with nominal composition of 51.2% CaO-12.1% MgO-36.7% SiO_2 (wt%) was synthesized. Then multiphase glass-ceramics of MGC1 and MGC2 were obtained by adding 1 and 2 wt% B_2O_3 to GCO followed by thermal treatment. The bending strength of MGC1 was the highest, about 89.46 MPa, and the coefficient of thermal expansion was 10.67 × 10~(-6) ℃~(-1), closer to that of Ti-6Al-4V alloy (10.03 × 10~(-6) ℃~(-1)). X-ray diffraction analysis confirmed that MGC1 was predominantly composed of akermanite, merwinite, and small amounts of dicalcium silicate crystalline phases. The bioactivity and cytocompatibility in vitro of MGC1 were detected by investigating the bonelike apatite-formation ability in simulated body fluid (SBF) and osteoblast morphology and viability. The results showed that MGC1 possessed bonelike apatite-formation ability in SBF and could release ionic products to significantly stimulate cell growth and viability. Furthermore, osteoblasts adhered and spread well on MGC1, indicating good bioactivity and potential cytocompatibility.
机译：合成了标称组成为51.2％CaO-12.1％MgO-36.7％SiO_2（wt％）的玻璃陶瓷（GCO）。然后通过向GCO中添加1和2 wt％B_2O_3，然后进行热处理，获得MGC1和MGC2的多相玻璃陶瓷。 MGC1的弯曲强度最高，约为89.46 MPa，热膨胀系数为10.67×10〜（-6）℃〜（-1），接近于Ti-6Al-4V合金（10.03×10〜 （-6）℃〜（-1））。 X射线衍射分析证实，MGC1主要由钙钛矿，皂石和少量的硅酸二钙结晶相组成。通过研究模拟体液（SBF）中的骨样磷灰石形成能力以及成骨细胞的形态和活力，检测了MGC1的体外生物活性和细胞相容性。结果表明，MGC1在SBF中具有骨样磷灰石形成能力，并且可以释放离子产物，从而显着刺激细胞生长和生存能力。此外，成骨细胞在MGC1上粘附并良好扩散，表明具有良好的生物活性和潜在的细胞相容性。

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