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Fabrication and characterization of gold nanoparticle-loaded TiO2 nanotube arrays for medical implants

机译:医用植入物负载金纳米颗粒的TiO2纳米管阵列的制备与表征

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摘要

Au nanoparticles (AuNPs) are successfully assembled on TiO2 nanotube (TN) arrays through electrochemical deposition technology to improve the surface characteristics of TN arrays as an implant material. The loading amount of AuNPs can be controlled by adjusting the deposition time of electrochemical deposition. The effect of the amount of the loaded AuNPs on surface roughness and surface energy is systematically investigated on the basis of various characterizations. Results show that the increase in the loading amount of AuNPs on the TN arrays can increase surface roughness and decrease surface energy. Potentiodynamic polarization tests indicate that AuNP-modified TNs possess a higher corrosion resistance than unmodified TNs. Corrosion resistance increases as the amount of the loaded AuNP increases. In vitro cell culture tests are performed on the basis of cell morphology observations and MTT assays. Osteoblast cell adhesion and proliferation ability on the AuNP-modified TN surface are greater than those on the unmodified TN surface. The sample fabricated at the deposition time of 90 s exhibits an optimum cell performance. This work can provide a new platform to develop the surface chemistry of TN arrays and to fabricate titanium-based implant materials to enhance bioactivity.
机译:通过电化学沉积技术将金纳米颗粒(AuNPs)成功地组装在TiO2纳米管(TN)阵列上,以改善作为植入材料的TN阵列的表面特性。 AuNPs的负载量可以通过调节电化学沉积的沉积时间来控制。根据各种表征,系统地研究了负载的AuNPs量对表面粗糙度和表面能的影响。结果表明,TN阵列上AuNPs的负载量增加可以增加表面粗糙度,降低表面能。电位动力学极化试验表明,AuNP改性的TNs比未改性的TNs具有更高的耐腐蚀性。耐腐蚀性随着AuNP的负载量的增加而增加。体外细胞培养测试是根据细胞形态学观察和MTT分析进行的。 AuNP修饰的TN表面上的成骨细胞粘附和增殖能力比未修饰的TN表面上的成骨细胞更大。在90 s的沉积时间制造的样品表现出最佳的电池性能。这项工作可以提供一个新的平台,以开发TN阵列的表面化学,并制造钛基植入材料以增强生物活性。

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  • 来源
    《Journal of materials science》 |2016年第2期|31.1-31.11|共11页
  • 作者单位

    Inner Mongolia Univ Technol, Sch Mat Sci & Engn, Hohhot 010051, Inner Mongolia, Peoples R China;

    Inner Mongolia Univ Technol, Sch Mat Sci & Engn, Hohhot 010051, Inner Mongolia, Peoples R China;

    Inner Mongolia Univ Technol, Sch Mat Sci & Engn, Hohhot 010051, Inner Mongolia, Peoples R China;

    Inner Mongolia Univ Technol, Sch Mat Sci & Engn, Hohhot 010051, Inner Mongolia, Peoples R China;

    Inner Mongolia Univ Technol, Sch Mat Sci & Engn, Hohhot 010051, Inner Mongolia, Peoples R China;

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