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首页> 外文期刊>Journal of materials science >Evaluation of the behaviour of fluorine-containing bioactive glasses: reactivity in a simulated body fluid solution assisted by multivariate data analysis
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Evaluation of the behaviour of fluorine-containing bioactive glasses: reactivity in a simulated body fluid solution assisted by multivariate data analysis

机译:评估含氟生物活性玻璃的行为:在模拟体液中的反应性(通过多元数据分析辅助)

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摘要

Potentially bioactive fluorine-containing glasses of formula 46.2SiO_2·24.3Na_2O·(26.9-x)CaO·2.6P_2O_5· xCaF_2 [x = (0), 5, 10, 15] have been studied: the study was carried out as a function of fluorine percentage, dimensions and time of soaking in SBF. The results are compared to those obtained in the same conditions for Bioglass~® 45S5. Due to the high number and different kind of variables/ conditions explored by this set of data, the results are rationalized for the first time by means of multivariate data analysis (MDA); in this way it is possible to classify the behaviour of bioglasses toward bioactivity. The presence of fluorine does not inhibit the formation of HA; in particular, for a fast bioactivity (in term of HA crystallization) it will be better to have large particle size or slabs, while for a fast dissolution fine particle sizes should be preferred.
机译:已研究了具有潜在生物活性的式46.2SiO_2·24.3Na_2O·(26.9-x)CaO·2.6P_2O_5·xCaF_2 [x =(0),5、10、15]的含氟玻璃:根据功能进行了研究SBF中氟的百分比,尺寸和浸泡时间。将结果与在相同条件下获得的Bioglass®45S5进行比较。由于该组数据探索的变量和条件种类繁多,因此首次通过多元数据分析(MDA)对结果进行了合理化;以这种方式可以对生物玻璃的生物活性进行分类。氟的存在不会抑制HA的形成。特别地,对于快速的生物活性(就HA结晶而言),具有大的粒径或大块将是更好的,而对于快速的溶解,应当优选细粒径。

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  • 来源
    《Journal of materials science》 |2012年第3期|639-648|共10页
  • 作者单位

    Department of Chemistry, University of Modena and Reggio Emilia, Via G. Campi 183, 41125 Modena, Italy;

    Department of Chemistry, University of Modena and Reggio Emilia, Via G. Campi 183, 41125 Modena, Italy;

    Department of Chemistry, University of Modena and Reggio Emilia, Via G. Campi 183, 41125 Modena, Italy;

    Department of Chemistry, University of Modena and Reggio Emilia, Via G. Campi 183, 41125 Modena, Italy;

    Department of Chemistry, University of Modena and Reggio Emilia, Via G. Campi 183, 41125 Modena, Italy;

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