• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of materials science >Ceramic/metal biocidal nanocomposites for bone-related applications
【24h】

Ceramic/metal biocidal nanocomposites for bone-related applications

机译：用于骨相关应用的陶瓷/金属杀菌纳米复合材料

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Hydroxyapatite/silver nanocomposites have been designed and synthesized as an engineering material for biomedical applications. The hydroxyapatite matrix was synthesized by a sol-gel method and, subsequently, the Ag nanoparticles were deposited by heterogeneous precipitation followed by two different reduction routes: thermal or chemical. Both sets were studied and compared and, in all cases, the metal nanoparticles appear perfectly isolated and attached to the surface of the hydroxyapatite. The average metal particle size is below 10 nm, allowing an important contact surface between silver and the microorganisms. The antimicrobial behavior against common bacteria showed a high effectiveness, well above the commercial level, as well as against yeast, in the case of the chemically reduced sample. Due to the nanocomposite microstructure, only a negligible portion of metal was released to the lixiviated liquid after the biocide tests, minimizing the risk of toxicity. These nanocomposites offer a solution to the infections on the surface of implants, one of the main problems in reaching a suitable level of osseointegration.
机译：羟基磷灰石/银纳米复合材料已被设计和合成为生物医学应用的工程材料。通过溶胶-凝胶法合成羟基磷灰石基体，随后，通过非均相沉淀，然后通过两种不同的还原途径：热或化学方法，沉积纳米银。两组都进行了研究和比较，并且在所有情况下，金属纳米颗粒似乎都完全隔离并附着在羟基磷灰石表面。金属的平均粒径在10 nm以下，从而使银与微生物之间形成重要的接触表面。在化学还原样品的情况下，对常见细菌的抗微生物行为表现出很高的效力，远高于商业水平，对酵母的抗微生物行为。由于具有纳米复合材料的微观结构，在杀菌剂测试后，只有极少部分的金属释放到了浸液中，从而最大程度地降低了毒性风险。这些纳米复合材料为植入物表面的感染提供了解决方案，这是达到合适的骨整合水平的主要问题之一。

著录项

  • 来源
    《Journal of materials science》 |2012年第7期|p.1655-1662|共8页
  • 作者

    Miriam Miranda; Adolfo Fernandez; Sonia Lopez-Esteban; Francisco Malpartida; Jose S. Moya; Ramon Torrecillas;

  • 作者单位

    Centra de Investigation en Nanomateriales y Nanotecnologia (CINN-CSIC-UO-PA), Parque Tecnologico de Asturias,33428 Llanera, Spain;

    ITMA Materials Technology, Llanera, Spain;

    Centra de Investigation en Nanomateriales y Nanotecnologia (CINN-CSIC-UO-PA), Parque Tecnologico de Asturias,33428 Llanera, Spain;

    Centro Nacional de Biotecnologfa (CNB-CSIC),28049 Cantoblanco, Spain;

    Institute de Ciencia de Materiales de Madrid (ICMM),Consejo Superior de Investigaciones Cientiflcas (CSIC),Cantoblanco, Spain;

    Centra de Investigation en Nanomateriales y Nanotecnologia (CINN-CSIC-UO-PA), Parque Tecnologico de Asturias,33428 Llanera, Spain;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号