...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of materials science >The effect of phosphate content on the bioactivity of soda-lime-phosphosilicate glasses
【24h】

The effect of phosphate content on the bioactivity of soda-lime-phosphosilicate glasses

机译：磷酸盐含量对钠钙磷酸盐硅酸盐玻璃生物活性的影响

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

We report on the bioactivity of two series of glasses in the SiO_2-Na_2O-CaO-P_2O_5 system after immersion in simulated body fluid (SBF) after 21 days. The effect of P_2O_5 content was examined for compositions containing 0-9.25 mol.% phosphate. Both series of glasses degraded to basic pH, but the solutions tended towards to neutrality with increasing phosphate content; a result of the acidic phosphate buffering the effect of the alkali metal and alkaline earth ions on degradation. Bioactivity was assessed by the appearance of features in the X-ray diffraction (XRD) traces and Fourier transform infrared (FTIR) spectra consistent with crystalline hydroxyl-carbonate-apatite (HCAp): such as the appearance of the (002) Bragg reflection in XRD and splitting of the P-O stretching vibration around 550 cm~(-1) in the FTIR respectively. All glasses formed HCAp in SBF over the time periods studied and the time for formation of this crystalline phase occurred more rapidly in both series as the phosphate contents were increased. For P_2O_5 content >3 mol.% both series exhibited highly crystalline apatite by 16 h immersion in SBF. This indicates that in the compositions studied, phosphate content is more important for bioactivity than network connectivity (NC) of the silicate phase and compositions showing rapid apatite formation arernpresented, superior to 45S5 Bioglass~® which was tested under identical conditions for comparison.
机译：我们报告了在SiO_2-Na_2O-CaO-P_2O_5系统中浸入模拟体液（SBF）21天后的两个系列玻璃的生物活性。对于含有0-9.25mol。％磷酸盐的组合物，检查了P_2O_5含量的影响。这两个系列的玻璃均降解至碱性pH，但随着磷酸盐含量的增加，溶液趋于中性。酸性磷酸盐缓冲了碱金属和碱土金属离子对降解的影响的结果。通过X射线衍射（XRD）痕迹的特征和与结晶羟基碳酸盐-磷灰石（HCAp）一致的傅里叶变换红外（FTIR）光谱中的特征的出现来评估生物活性：例如在（002）布拉格反射的出现FTIR分别在550 cm〜（-1）附近进行XRD和PO的拉伸振动分裂。在所研究的时间段内，所有玻璃均在SBF中形成了HCAp，并且随着磷酸盐含量的增加，在两个系列中形成此晶相的时间都更快。当P_2O_5含量> 3 mol。％时，两个系列在SBF中浸泡16 h都显示出高结晶磷灰石。这表明在所研究的组合物中，磷酸盐含量对生物活性比硅酸盐相的网络连通性（NC）更为重要，并且呈现出快速磷灰石形成的组合物，优于在相同条件下进行测试以进行比较的45S5Bioglass®。

著录项

  • 来源
    《Journal of materials science》 |2009年第8期|1611-1618|共9页
  • 作者

    M. D. ODonnell; S. J. Watts; R. G. Hill; R. V. Law;

  • 作者单位

    Department of Materials, Imperial College London, London, UK Department of Chemistry, Imperial College London, London, UK BioCeramic Therapeutics Ltd., London, UK;

    Department of Materials, Imperial College London, London, UK Department of Chemistry, Imperial College London, London, UK BioCeramic Therapeutics Ltd., London, UK;

    Department of Materials, Imperial College London, London, UK Department of Chemistry, Imperial College London, London, UK BioCeramic Therapeutics Ltd., London, UK;

    Department of Materials, Imperial College London, London, UK Department of Chemistry, Imperial College London, London, UK BioCeramic Therapeutics Ltd., London, UK;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号