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首页> 外文期刊>Journal of Nanjing Medical University >Transcatheter to Close the Patent Ductus Arteri-osus and Atrial Septal Defects in Children
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Transcatheter to Close the Patent Ductus Arteri-osus and Atrial Septal Defects in Children

机译：经导管闭合儿童的动脉导管未闭和房间隔缺损

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Objective: To evaluate the therapeutic effect, safety and complications of transcathetering Amplatzer device in the closure of patent ductus arteriosus (PDA) and atrial septal defects (ASD) in children. Methods: Patients with PDA (n = 25) and ASD ( n = 16), confirmed by echocardiography, were treated by transcatheterization. Amplatzer occluder device was placed by the transcatheterization with the image support of X-ray and transthoracic echocardiography ( TTE) . The TTE, ECG and X-ray examination were engaged to evaluate the therapeutic results on the time points of 24 h , 1, 3 , 6, 12 months after the operation, and all these cases were engaged to the follow-up examination. Results: The cardioangiographic diameter was 13.0-28.0 mm ([19.3+-4.9] mm) in ASD and 2.0-7.7 mm ([3.9+-1.5] mm) in PDA . The diameter of the Amplatzer occluder selected were 13.0-30.0 mm ( [20.6+-5.1] mm) in ASD and 4.0-12.0 mm ([6.6+-1.9] mm) in PDA , respectively. All the Amplatzer occluders were placed successfully. There were no complications during and after the operation. Very small residual shunt was still found soon after the operation in 10 cases , and there were no residual or recanalization after three months of the operation. The pulmonary artery pressure and heart size were significantly decreased in follow-up examination . Conclusion: Transcathetering closure with Amplatzer device is an effective, simple and safe technique in the treatment of ASD and PDA in children.
机译：目的：评价经导管Amplatzer装置封闭儿童动脉导管未闭（PDA）和房间隔缺损（ASD）的疗效，安全性和并发症。方法：经超声心动图检查证实的PDA（n = 25）和ASD（n = 16）患者经导管置入术治疗。通过X射线图像支架和经胸超声心动图（TTE）进行经导管置入放置Amplatzer封堵器装置。分别在术后24、1、3、6、12个月的时间点进行TTE，ECG和X线检查，以评估治疗结果，并对所有这些病例进行随访检查。结果：在ASD中，心血管造影直径为13.0-28.0 mm（[19.3 + -4.9] mm），在PDA中为2.0-7.7 mm（[3.9 + -1.5] mm）。选择的Amplatzer封堵器的直径在ASD中为13.0-30.0 mm（[20.6 + -5.1] mm），在PDA中为4.0-12.0 mm（[6.6 + -1.9] mm）。所有Amplatzer封堵器均已成功放置。术中及术后无并发症。术后10例仍发现很小的残余分流，术后3个月无残余或再通。在随访检查中，肺动脉压力和心脏大小均明显降低。结论：Amplatzer装置经导管封闭术是治疗儿童ASD和PDA的有效，简单和安全的技术。

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