首页> 外文期刊>Journal of Nanjing Medical University >Expression of Interleukin-13 in Peripheral Blood Mononuclear Cells from Patients With Nephrotic Syndrome
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Expression of Interleukin-13 in Peripheral Blood Mononuclear Cells from Patients With Nephrotic Syndrome

机译:肾病综合征患者外周血单个核细胞中白细胞介素13的表达

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摘要

Nephrotic syndrome (NS) is a kind of renal diseases characterized mainly by proteinuria and hypoalbuminemia. The disturbance of cellular immunity plays a major role in the pathogenesis of NS. The change of interleukin (IL)-13 produced by Th2 cells was investigated I 50 chldren with NS. Methods All the patients were selected during their nephrotic stage and remis - sion stage. The expression of IL-13 protein and mRNA was determined by ELISA and reverse tran - scription-polymerase chain reaction (RT-PCR) respectively.
机译:肾病综合征(NS)是一种主要以蛋白尿和低白蛋白血症为特征的肾脏疾病。细胞免疫的障碍在NS的发病机理中起主要作用。用NS对50岁儿童研究了Th2细胞产生的白介素(IL)-13的变化。方法对所有患者在肾病期和缓解期进行选择。分别通过ELISA和逆转录聚合酶链反应(RT-PCR)测定IL-13蛋白和mRNA的表达。

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