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首页> 外文期刊>Journal of nano research >Synthesize and Characterization of Multifunctional Silica Coated Magnetic Nanoparticles using Polyvinylpyrrolidone (PVP) as a mediator
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Synthesize and Characterization of Multifunctional Silica Coated Magnetic Nanoparticles using Polyvinylpyrrolidone (PVP) as a mediator

机译：聚乙烯吡咯烷酮（PVP）为介体的多功能二氧化硅包覆磁性纳米粒子的合成与表征

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摘要

Magnetic iron oxide nanoparticles with proper surface coatings are increasingly being evaluated for clinical applications such as hyperthermia, drug delivery, magnetic resonance imaging, transfection and cell/protein separations. In this work, silica coated iron oxide magnetic nanoparticles, which are very useful for delivering chemotherapeutic drugs, has been prepared by precipitation in an aqueous solution of iron (II) and iron (III) chlorides under basic condition. In this process, polyvinylpyrrolidone (PVP) has been used as a stablizer. Surface modifications of the as-prepared Fe_3O_4 Nps have been carried out by using tetraethoxysilane (TEOS). Silica coated nanoparticles have been characterized by Fourier transform infrared (FTIR) spectroscopy, Powder X- ray diffraction (XRD), Transmission electron microscopy (TEM) and Infrared (IR) spectroscopy
机译：具有适当表面涂层的磁性氧化铁纳米粒子正越来越多地被评估用于临床应用，例如热疗，药物输送，磁共振成像，转染和细胞/蛋白质分离。在这项工作中，已经通过在碱性条件下在氯化铁（II）和氯化铁（III）的水溶液中沉淀制备了二氧化硅涂层的氧化铁磁性纳米颗粒，这些颗粒对递送化疗药物非常有用。在此过程中，聚乙烯吡咯烷酮（PVP）已用作稳定剂。通过使用四乙氧基硅烷（TEOS）对所制备的Fe_3O_4 Nps进行了表面改性。二氧化硅包覆的纳米颗粒已经通过傅里叶变换红外（FTIR）光谱，粉末X射线衍射（XRD），透射电子显微镜（TEM）和红外（IR）光谱进行了表征

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  • 来源
    《Journal of nano research》 |2011年第2011期|p.43-48|共6页
  • 作者

    M.S. Sadjadi; F. Fathi; N. Farhadyar; K.Zare;

  • 作者单位

    Department of Chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran;

    Department of Chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran;

    Department of Chemistry, Varamin -Pishva Branch, Islamic Azad University, Tehran, Iran;

    Department of Chemistry, Shahid Beheshti University,Tehran, Iran;

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  • 原文格式 PDF
  • 正文语种 eng
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  • 关键词

    magnetic iron oxide; surface modification; polyvinylpyrrolidone;

    机译：磁性氧化铁表面改性;聚乙烯吡咯烷酮;

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