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首页> 外文期刊>Journal of Parasitology >Seasonal Fluctuations of Incubation, Healing Delays, and Clinical Presentation of Cutaneous Leishmaniasis in French Guiana
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Seasonal Fluctuations of Incubation, Healing Delays, and Clinical Presentation of Cutaneous Leishmaniasis in French Guiana

机译：法属圭亚那的温育季节的季节性波动，治疗延迟和皮肤利什曼病的临床表现

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摘要

An investigation was conducted to determine whether seasonal variations affected the development of cutaneous leishmaniasis. Data from 499 cases treated between July 1994 and December 1998 were analyzed. The interval between infection and consultation and between treatment and clinical cure varied significantly between cases with an incubation period during the dry season compared with the rainy season (P < 0.001). When the incubation period occurred during the dry season, the standard pentamidine isethionate treatment seemed to be less effective (i.e., the odds ratio for failure was 1.9 [1.1–3.4], P = 0.01). The presence of lymphangitis was more frequent during the dry season (i.e., the odds ratio was 0.26 [0.15–0.45]m P < 0.001). These results suggested that the observed seasonal variations were due to variations in the host/parasite balance. Converging indirect elements that suggest a role for variations in solar ultraviolet radiation are discussed.
机译：进行了一项调查以确定季节性变化是否影响皮肤利什曼病的发展。分析了1994年7月至1998年12月期间治疗的499例病例的数据。与雨季相比，在干燥季节有潜伏期的病例之间，感染与咨询之间的间隔以及治疗与临床治愈之间的间隔差异显着（P <0.001）。当潜伏期是在干燥季节时，标准的喷他is异羟乙磺酸盐处理似乎效果较差（即失败的几率是1.9 [1.1-3.4]，P = 0.01）。在干燥季节，淋巴管炎的存在更为频繁（即，比值比为0.26 [0.15-0.45] m P <0.001）。这些结果表明，观察到的季节性变化是由于宿主/寄生虫平衡的变化所致。讨论了暗示间接影响太阳紫外线辐射的作用的会聚间接元素。

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    《Journal of Parasitology》 |2001年第6期|p.00001495-00001498|共4页
  • 作者

    M. Nachera B. Carmeb D. Sainte Mariea P. Couppiéa E. Clytia P. Guiberta and R. Pradinauda;

  • 作者单位

    aService de Dermatologie Vénérologie, Centre Hospitalier de Cayenne, rue des flamboyants, 97300 Cayenne, Guyane FrançaisebService de Parasitologie-Mycologie, Equipe JE 21-88, UFR de Médecine des Antilles et de la Guyane et Centre Hospitalier de Cayenne, Campus Saint Denis, BP 718-97306 Cayenne, Guyane Française. m_nacher@mailcity.com;

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