...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Parasitology >MECHANISMS UNDERLYING DIGENEAN–SNAIL SPECIFICITY: ROLE OF MIRACIDIAL ATTACHMENT AND HOST PLASMA FACTORS
【24h】

MECHANISMS UNDERLYING DIGENEAN–SNAIL SPECIFICITY: ROLE OF MIRACIDIAL ATTACHMENT AND HOST PLASMA FACTORS

机译：DIGENEAN-SNAIL特殊性的机制：微小的附着和宿主血浆因子的作用

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Digenetic trematodes usually show a high degree of specificity for their molluscan intermediate hosts. A panel of 4 digenean species (Echinostoma paraensei, E. trivolvis, Schistosoma mansoni, and Schistosomatium douthitti) and 5 snail species (Biomphalaria glabrata, Helisoma trivolvis, Lymnaea stagnalis, Stagnicola elodes, and Helix aspersa representing 3 gastropod families) was used to assess the relative contributions of miracidial behavior, host plasma osmolality, and host plasma factors in dictating specificity. Additional experiments were undertaken with a fifth digenean, Echinoparyphium sp. Expected patterns of compatibility were first confirmed; each parasite species produced patent infections in its known snail host, but not in the other snail species. One exception was S. douthitti, which unexpectedly did not infect L. stagnalis. As judged by direct observation and by noting their disappearance after exposure to snails, miracidia were generally less likely to attach to or penetrate incompatible than compatible hosts. However, over half of the miracidia of each parasite species attached to or attempted penetration of both compatible and incompatible hosts, suggesting that under the experimental conditions used, miracidial host location and attachment behaviors were not of overriding importance in dictating observed patterns of specificity. For each digenean species, the percentage of larvae that became immobile, rounded, showed tegumental damage, or died over a 6-hr interval in plasma of the various snails was assessed. In no case was plasma from a compatible host harmful to sporocysts or rediae. In contrast, in 8 of 16 (50 %) incompatible combinations, snail plasma had a significant negative effect on sporocyst condition. In 4 of 12 (33%) incompatible combinations, plasma had a significant negative effect on rediae. In 9 of 10 combinations tested, lymnaeid plasma was toxic for the parasites of planorbid snails and in 2 of 4 combinations, planorbid plasma was toxic for the parasites of lymnaeid snails. Toxicity was not attributable to differences in plasma osmolality between snail species. The ability of plasma from incompatible snails to affect viability of both sporocysts and rediae was surprisingly strong, suggesting that humoral factors play a greater role in dictating patterns of digenean–snail specificity than previously appreciated.
机译：双基因吸虫通常对它们的软体动物中间宿主表现出高度的特异性。分别使用了代表3个腹足动物科的4种双属植物物种（棘皮棘皮chin，三角肠埃希菌，曼氏血吸虫和曼氏血吸虫和杜氏血吸虫）和5种蜗牛物种（光滑小球藻，Helisoma trivolvis，剑叶，gn木，螺tag和螺旋螺）。 miracidial行为，宿主血浆渗透压和宿主血浆因素在指示特异性方面的相对贡献。用第五种双属植物Echinoparyphium sp。进行了另外的实验。首先确认了预期的兼容性模式；每个寄生虫物种在其已知的蜗牛宿主中均产生了专利感染，而在其他蜗牛物种中则没有。杜氏葡萄球菌（S. douthitti）是一个例外，它出乎意料地没有感染stagnalis。通过直接观察并注意到它们在暴露于蜗牛后消失后判断，与同适应的宿主相比，水母通常更不可能附着或穿透不相容的宿主。但是，每种寄生虫物种的半数以上的狂潮症都与相容性和不相容性寄主相连或试图穿透，这表明在所使用的实验条件下，对于指示观察到的特异性模式，性寄主的位置和附着行为并不是最重要的。对于每种双基因动物，评估了在各种蜗牛血浆中在6小时间隔内变得固定，变圆，被表皮损伤或死亡的幼虫百分比。兼容宿主的血浆在任何情况下都不会危害孢子囊或重症。相反，在16个不相容的组合中有8个（50％），蜗牛血浆对孢子囊状况有明显的负面影响。在12种不相容的组合中，有4种（33％）血浆对重做具有明显的负面影响。在所测试的10种组合中的9种中，lymnaeid血浆对蜗牛的寄生虫有毒，而在4种组合中的2种中，planorbid血浆对lymnaeid蜗牛的寄生虫有毒。毒性不归因于蜗牛之间血浆渗透压的差异。来自不相容蜗牛的血浆影响孢子囊和重做细胞活力的能力出奇地强，这表明体液因素在决定双基因-蜗牛特异性模式中起着比以前更重要的作用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号