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首页> 外文期刊>Journal of Polymers and the Environment >Ultrastructural, Morphological, and Antifungal Properties of Micro and Nanoparticles of Chitosan Crosslinked with Sodium Tripolyphosphate
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Ultrastructural, Morphological, and Antifungal Properties of Micro and Nanoparticles of Chitosan Crosslinked with Sodium Tripolyphosphate

机译：三聚磷酸钠交联的壳聚糖微粒和纳米颗粒的超微结构，形态和抗真菌特性

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摘要

Recent studies have demonstrated the antibacterial effect of micro and nanoparticles of chitosan (CS) crosslinked with sodium tripolyphosphate (TPP), and incorporating metallic ions, bringing that the size, shape, and zeta potential are related to the antimicrobial potential. However, there are few studies on the antifungal activity and the effect of TPP on the antimicrobial potential. Micro and nanoparticles were prepared from CS by ionotropic gelation with TPP, and structurally characterized by transmission and scanning electron spectroscopy, and Fourier transformed infrared spectroscopy. Depending on the concentration of CS and TPP, spherical particles were obtained from 80 nm to 20 μm. Subsequently, particles were evaluated for their antifungal potential against Aspergillus parasiticus assessing radial growth, spore germination, and morphological changes. An increase in the antifungal potential compared with CS in solution was observed, inhibiting the development of the fungus causing clear morphological changes in both, hyphae and spores. Particle size and the availability of functional groups of CS/TPP (amino group and phosphate), suggest a possible synergistic effect between CS and TPP.
机译：最近的研究表明，与三聚磷酸钠（TPP）交联的壳聚糖（CS）的微米和纳米颗粒的抗菌作用，并掺入金属离子，从而使其大小，形状和Zeta电位与抗菌潜力有关。但是，关于抗真菌活性和TPP对抗菌潜能的影响的研究很少。通过与TPP进行离子凝胶法从CS制备微颗粒和纳米颗粒，并通过透射和扫描电子光谱以及傅里叶变换红外光谱对结构和特征进行表征。根据CS和TPP的浓度，可以得到80nm至20μm的球形颗粒。随后，评估颗粒对寄生曲霉的抗真菌潜力，评估放射状生长，孢子萌发和形态变化。观察到与CS相比，溶液中的抗真菌潜力增加，抑制了真菌的生长，引起菌丝和孢子的明显形态变化。 CS / TPP的官能团（氨基和磷酸盐）的粒径和可用性表明，CS和TPP之间可能存在协同作用。

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