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首页> 外文期刊>Journal of porous materials >Enhancement of carbonate apatite scaffold properties with surface treatment and alginate and gelatine coating
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Enhancement of carbonate apatite scaffold properties with surface treatment and alginate and gelatine coating

机译：用表面处理和藻酸盐和明胶涂层增强碳酸盐磷灰石支架性能

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Carbonate apatite (CO(3)Ap) scaffolding has been widely used for bone repair and replacement due to its excellent osteoconductivity and resorbability in bone defects. However, the application of the porous scaffold has been limited by its brittleness. Here, CO(3)Ap scaffolds coated with 1, 3 and 5 wt% of sodium alginate (SA) and bovine gelatine (BG) were fabricated to improve the mechanical properties of the porous scaffold. Limited studies have been done on a CO(3)Ap scaffold coated with a natural polymer layer. Here, a CO(3)Ap scaffold was fabricated through the phase transformation from beta-tricalcium phosphate (beta-TCP) to CO(3)Ap using a hydrothermal method. Fourier-transform infrared (FTIR) analysis confirmed the presence of both SA and BG functional groups on the CO(3)Ap scaffold. Five wt% of SA and BG improved the compressive strength of the uncoated CO(3)Ap scaffold by 34% and 46%, respectively. The SA coating was found to enhance the compressive strength of the CO(3)Ap scaffold compared to the BG coating due to its high viscosity. Furthermore, the compressive strength of the scaffold increased by 40% after undergoing a silanization process and being coated with SA. These results indicate that the use of a silane treatment improved the chemical bonding between the CO(3)Ap scaffold and SA coating. This process increased the adhesion between the SA coating and the scaffold and improved the compressive strength.
机译：碳酸盐磷灰石（CO（3）AP）支架已广泛用于骨修复和替代性，因为其骨缺损的优异骨导电性和可再吸收性。然而，多孔支架的应用受其脆性的限制。这里，制备涂有1,3和5wt％的藻酸钠（SA）和牛明胶（BG）的CO（3）AP支架，以改善多孔支架的机械性能。在涂有天然聚合物层的CO（3）AP支架上已经完成了有限的研究。这里，通过使用水热法通过从β-三磷酸钙（β-TCP）至CO（3）AP的相变，制成CO（3）AP支架。傅里叶变换红外（FTIR）分析证实了CO（3）AP支架上的SA和BG官能团的存在。五重量％的SA和BG将未涂覆的CO（3）AP支架的抗压强度分别提高了34％和46％。发现SA涂层增强CO（3）AP支架的抗压强度与其高粘度引起的与Bg涂层相比。此外，在经历硅烷化过程并用SA涂覆后，支架的抗压强度增加了40％。这些结果表明，使用硅烷处理改善了CO（3）AP支架和SA涂层之间的化学键合。该过程增加了SA涂层和支架之间的粘附性，并提高了抗压强度。

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