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首页> 外文期刊>Journal of Sports Medicine and Physical Fitness >Pre-exercise oral creatine ingestion does not improve prolonged intermittent sprint exercise in humans
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Pre-exercise oral creatine ingestion does not improve prolonged intermittent sprint exercise in humans

机译：运动前口服肌酸并不能改善人类长时间的间歇性短跑运动

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Background. This investigation determined whether pre-exer-cise oral Cr ingestion could enhance prolonged intermittent sprint exercise performance. Methods. Experimental design: a randomised, double-blind crossover design was employed. Setting: testing was performed at the Western Australian Institute of Sport and participants were monitored and treated by both scientific and medical personnel. Participants: eight active, but not well-trained males with a background in multiple-sprint based sports acted as subjects for this investigation. Interventions: subjects ingested either 15 g Cr·H_2O or placebo 120 min and 60 min prior to the start of an 80-min maximal sprint cycling task (10 sets of multiple 6-sec sprints with varying active recoveries). Subjects were retested 14 days later, being required to ingest the alternate supplement and repeat the exercise test. Measures: performance variables (work done and peak power) were obtained throughout the exercise challenge. Muscle biopsies (vastus lateralis) were taken preexercise as well as immediately and 3 min post-exercise in order to determine concentrations of ATP, PCr, Cr, La~- and glycogen. Venous blood was drawn prior to and on four occasions during the exercise test, and analysed for Cr, NH_3~+, La~- and pH. Results. Serum Cr concentrations were raised to a peak of 2348+-223 μmol·l~(-1) prior to the commencement of exercise after Cr ingestion. There were no significant changes in any cycling performance parameters following Cr ingestion, although blood La~- was significantly lower (p<0.05) than placebo at all time points during exercise, and plasma NH_3~+ accumulation was also significantly reduced (p<0.05) in the Cr condition, but only in the second half of the 80-min exercise test. Muscle ATP and TCr levels as well as postexercise PCr replenishment were unaffected following Cr administration. Conclusions. The data suggest that although the pre-exercise ingestion of a large Cr dose was shown to have some impact on blood borne metabolites, it does not improve maximal prolonged intermittent sprint exercise performance, possibly due to an insufficient time allowed for uptake of serum Cr by skeletal muscle to occur. Therefore, this form of loading does not provide an alternative method of Cr supplementation to the traditional five-day supplementation regimes established by previous research.
机译：背景。这项研究确定了运动前口服铬的摄入是否可以增强长时间的间歇性短跑运动表现。方法。实验设计：采用随机，双盲交叉设计。地点：测试是在西澳大利亚体育学院进行的，参与者由科学和医疗人员进行监控和治疗。参加者：八名活跃但未受过良好训练的男性，其背景是基于多次短跑的运动，是本次调查的对象。干预措施：受试者在开始80分钟最大冲刺循环任务（10组多次6秒冲刺，具有不同的活动恢复）之前，分别在120分钟和60分钟之前摄入15 g Cr·H_2O或安慰剂。 14天后对受试者进行了重新测试，需要摄入替代品并重复运动测试。措施：在整个运动挑战中获得性能变量（完成的工作和峰值功率）。在运动前和运动后以及运动后3分钟进行肌肉活检（外侧输卵管），以确定ATP，PCr，Cr，La〜-和糖原的浓度。在运动试验之前和运动试验期间四次抽血，并分析其Cr，NH_3〜+，La〜-和pH。结果。摄入铬后开始运动前，血清中铬的浓度升高至峰值2348 + -223μmol·l〜（-1）。铬摄入后，任何循环性能参数均无显着变化，尽管运动期间所有时间点血液La〜-显着低于安慰剂（p <0.05），血浆NH_3〜+积累也显着减少（p <0.05） ）在Cr条件下进行，但仅限于80分钟运动测试的后半段。施用Cr后，肌肉ATP和TCr水平以及运动后PCr补充均不受影响。结论。数据表明，虽然运动前摄入大剂量的铬对血液中的代谢产物有一定影响，但它并不能改善最大的间歇性短跑运动时间，这可能是由于时间不足以使铬吸收血清铬所致。骨骼肌发生。因此，这种形式的负载不能为先前研究建立的传统的五天补充方案提供另一种补充铬的方法。

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