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首页> 外文期刊>The Journal of the Textile Institute >Bacteriological effects of functionalized cotton dressings
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Bacteriological effects of functionalized cotton dressings

机译：功能化棉花敷料的细菌学效应

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This study aims to achieve effects of improved hydrophilicity and microorganism inhibition, which are rarely simultaneously present in wound dressings. Cotton gauzes were modified using the grafting of a polymer-based beta-cyclodextrin. After optimizing the grafting conditions, the untreated and modified cellulosic samples were principally characterized using FT-IR spectroscopy, TGA/DTA analysis, in vitro drug release, and wettability measurements. In light of desired characteristics of wound dressings, the effectiveness of procedures was evaluated. It was found that contact angles for cotton gauzes decreased after functionalization, which means that hydrophilicity was proven to become excellent. A successful Methylene Blue complexation was confirmed through measure of the dyebath exhaustion using UV-spectrophotometry. Then, during Methylen Blue release test, we reported an initial burst release of active ingredient over 7 h, followed by zero-order release. The treatment effect on antimicrobial activity was investigated by growth inhibition, which was proven against Staphylococcus aureus and Escherichia coli.
机译：这项研究旨在获得改善的亲水性和抑制微生物的效果，而这些效果很少同时出现在伤口敷料中。使用基于聚合物的β-环糊精的接枝修饰棉纱网。优化接枝条件后，主要使用FT-IR光谱，TGA / DTA分析，体外药物释放和润湿性测量来表征未经处理和改性的纤维素样品。根据伤口敷料的所需特性，评估了程序的有效性。发现在功能化之后，棉纱网的接触角减小，这意味着亲水性被证明是优异的。通过使用紫外分光光度法测量染浴消耗量，可以确认成功的亚甲基蓝络合物。然后，在亚甲基蓝释放测试中，我们报告了活性成分在7小时内首次爆发释放，然后是零级释放。通过生长抑制研究了其对抗菌活性的治疗作用，该抑制作用被证明对金黄色葡萄球菌和大肠杆菌具有抑制作用。

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