Hydrophobically Assisted Switching Phase Synthesis:The Flexible Combination of Solid-Phase and Solution-Phase Reactions Employed for Oligosaccharide Preparation

Jorg Bauer; Jorg Rademann

首页> 外文期刊>Journal of the American Chemical Society >Hydrophobically Assisted Switching Phase Synthesis:The Flexible Combination of Solid-Phase and Solution-Phase Reactions Employed for Oligosaccharide Preparation

【24h】

Hydrophobically Assisted Switching Phase Synthesis:The Flexible Combination of Solid-Phase and Solution-Phase Reactions Employed for Oligosaccharide Preparation

机译：疏水辅助的开关相合成：寡糖制备固相和固相反应的灵活结合

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Polymer-supported oligosaccharide synthesis has been for more than three decades one of the most challenging fields for solid-phase chemistry.Though progress has been made by the introduction of mildly activated carbohydrate donors and rugged linker chemistries,the reported yields for repetitive glycosylations are still unsatisfactory and the preparation of oligosaccharide-based libraries has hardly ever been realized.

机译：聚合物支持的寡糖合成已超过三十年，一直是固相化学领域最具挑战性的领域之一。尽管通过引入轻度活化的碳水化合物供体和坚固的连接基化学已取得了进展，但据报道重复糖基化的收率仍然很高令人满意的是，基于寡糖的文库的制备几乎从未实现过。

著录项

来源
《Journal of the American Chemical Society》 |2005年第20期|p.7296-7297|共2页
作者
Jorg Bauer; Jorg Rademann;
展开▼
作者单位

Leibniz Institute for Molecular Pharmacology (FMP),13125 Berlin,Germany,Institute for Chemistry,Organic Chemistry,Free University of Berlin,14195 Berlin,Germany,and Institute for Organic Chemistry,Eberhard-Karls-University Tubingen,72076 Tubingen,Ger;

Leibniz Institute for Molecular Pharmacology (FMP),13125 Berlin,Germany,Institute for Chemistry,Organic Chemistry,Free University of Berlin,14195 Berlin,Germany,and Institute for Organic Chemistry,Eberhard-Karls-University Tubingen,72076 Tubingen,Ger;

展开▼
收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类化学;
关键词

相似文献

外文文献
中文文献
专利

1. Convergent synthesis of oligosaccharides on the gram-scale using cetyl thioglycoside based on a hydrophobically assisted switching phase method [J] . Shuai Meng, Tian Tian, Yun-He Wang, Organic & biomolecular chemistry . 2016,第32期

机译：十六烷基硫代糖苷基于疏水辅助开关相法的克级聚合寡糖合成
2. Optimization of microwave-assisted solid-phase oligosaccharides synthesis reaction and analysis of components and structure of synthetic product [J] . Xin-Ming Li, Guo-Wei Le, Jing-Xiong Cheng, Carbohydrate Polymers: Scientific and Technological Aspects of Industrially Important Polysaccharides . 2006,第3期

机译：微波辅助固相寡糖合成反应的优化及合成产物的组成和结构分析
3. Microwave-assisted solid-phase oligosaccharides synthesis reaction and scavenging activity of synthetic product to free radical [J] . Xin-Ming Li, Guo-Wei Le, Yong-Hui Shi Carbohydrate Polymers: Scientific and Technological Aspects of Industrially Important Polysaccharides . 2006,第2期

机译：微波辅助固相寡糖的合成反应及合成产物清除自由基的活性
4. Unprotected Oligosaceharides as Phase Tags for Solution-Phase Glycopeptide Synthesis with Solid-Phase Workup [C] . Zhongwu Guo American Chemical Society . 2005

机译：非保护的寡核苷酸作为溶液相糖肽合成的相位标签，具有固相次处理
5. Nonaqueous biocatalysis in the synthesis of focused diversity: Solution-phase doxorubicin libraries and solid-phase peptide synthesis. [D] . Altreuter, David Henry. 2001

机译：非水生物催化合成中的重点多样性：溶液相阿霉素库和固相肽合成。
6. Plate-to-Plate Fluorous Solid-Phase Extraction for Solution-Phase Parallel Synthesis [O] . Wei Zhang, Yimin Lu, Tadamichi Nagashima -1

机译：用于溶液相平行合成的板对板氟固相萃取
7. Hydrophobically Assisted Switching Phase Synthesis: The Flexible Combination of Solid-Phase and Solution-Phase Reactions Employed for Oligosaccharide Preparation [O] . -1

机译：疏水辅助切换相合成：用于寡糖制剂的固相和溶液相反应的柔性组合

Hydrophobically Assisted Switching Phase Synthesis:The Flexible Combination of Solid-Phase and Solution-Phase Reactions Employed for Oligosaccharide Preparation

摘要

著录项

相似文献

相关主题

期刊订阅