• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Ultrasound >The efficacy and safety of endoscopic ultrasound‑guided liver biopsy versus percutaneous liver biopsy in patients with chronic liver disease: a retrospective single‑center study
【24h】

The efficacy and safety of endoscopic ultrasound‑guided liver biopsy versus percutaneous liver biopsy in patients with chronic liver disease: a retrospective single‑center study

机译：内镜超声引导下肝活检与经皮肝活检在慢性肝病患者中的有效性和安全性：一项回顾性单中心研究

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background and aims There is limited literature on endoscopic ultrasound-guided liver biopsy (EUS-LB), a new methodof obtaining liver biopsy (LB).Methods We conducted a retrospective study of the efficacy and safety of EUS-LB compared to percutaneous liver biopsy(PC-LB) in patients with chronic liver disease at our center between January 2018 and August 2019.Results Thirty patients underwent EUS-LB and 60 patients underwent PC-LB were identified (median follow-up post-LBwas 8 days; interquartile range (IQR), 3–5 days). The median number of portal tracts was significantly higher in the PC-LBgroup (13 vs. 5; P < 0.0001). A histologic diagnosis was established in 93% of the EUS-LB group, compared to 100% in thePC-LB group (P = 0.841). Patients in EUS-LB group had significantly shorter hospital stay (median time of hospital staywas 3 vs. 4.2 h in the EUS-LB vs. PC-LB group, respectively; P = 0.004) and reported less pain compared to PC-LB group(median pain score was 0 vs. 3.5; P = 0.0009). EUS-LB were performed using a 19-gauge (n = 27) or 22-gauge (n = 3); therewas a tendency towards higher number of portal tracts in the 22- vs. the 19-gauge needle group (6 vs. 5; P = 0.501). Nopatient in either group had significant adverse events such as bleeding or death.Conclusion EUS-LB is safe and is associated with less pain, shorter hospital stay, and high diagnostic yield (93%) comparedto PC-LB. Randomized trials are needed to standardize the utility of EUS-LB.
机译：背景与目的内镜超声引导下肝活检（EUS-LB）是一种获得肝活检（LB）的新方法，目前文献很少。方法我们对EUS-LB与经皮肝活检相比的有效性和安全性进行了回顾性研究。在我们中心于2018年1月至2019年8月期间对慢性肝病患者（PC-LB）进行分析。结果确定了30例接受EUS-LB的患者和60例接受PC-LB的患者（LB术后8天的中位随访;四分位差（IQR），3-5天）。 PC-LB组中门静脉束的中位数显着更高（13 vs. 5; P <0.0001）。在EUS-LB组中有93％建立了组织学诊断，而在PC-LB组中则为100％（P = 0.841）。 EUS-LB组患者的住院时间明显缩短（EUS-LB与PC-LB组的中位住院时间分别为3小时和4.2小时; P = 0.004），并且与PC-LB组相比，疼痛减轻了（中位疼痛评分为0 vs. 3.5; P = 0.0009）。 EUS-LB使用19规格（n = 27）或22规格（n = 3）进行;在22针和19针的针组中，门脉的数量倾向于增加（6对5; P = 0.501）。两组均无患者发生严重的不良事件，如出血或死亡。结论与PC-LB相比，EUS-LB是安全的，并且疼痛更少，住院时间更短，诊断率较高（93％）。需要随机试验来标准化EUS-LB的效用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号