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Accurate validation of ultrasound imaging of prostate cancer: a review of challenges in registration of imaging and histopathology

机译:前列腺癌超声成像的准确验证:成像和组织病理学注册方面的挑战综述

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摘要

As the development of modalities for prostate cancer (PCa) imaging advances, the challenge of accurate registration between images and histopathologic ground truth becomes more pressing. Localization of PCa, rather than detection, requires a pixel-to-pixel validation of imaging based on histopathology after radical prostatectomy. Such a registration procedure is challenging for ultrasound modalities; not only the deformations of the prostate after resection have to be taken into account, but also the deformation due to the employed transrectal probe and the mismatch in orientation between imaging planes and pathology slices. In this work, we review the latest techniques to facilitate accurate validation of PCa localization in ultrasound imaging studies and extrapolate a general strategy for implementation of a registration procedure.
机译:随着前列腺癌(PCa)成像方式的发展,图像与组织病理学基本事实之间准确配准的挑战变得更加紧迫。 PCa的定位而不是检测需要根治性前列腺切除术后根据组织病理学对图像进行逐像素验证。这种注册程序对超声检查方式具有挑战性。不仅必须考虑切除后的前列腺变形,而且还要考虑由于使用的经直肠探针以及成像平面和病理切片之间的方向不匹配而引起的变形。在这项工作中,我们将回顾最新技术,以促进超声成像研究中PCa定位的准确验证,并推断出实施注册程序的一般策略。

著录项

  • 来源
    《Journal of Ultrasound》 |2018年第3期|197-207|共11页
  • 作者单位

    Laboratory of Biomedical Diagnostics, Department of Electrical Engineering, Eindhoven University of Technology;

    Laboratory of Biomedical Diagnostics, Department of Electrical Engineering, Eindhoven University of Technology;

    Department of Urology, Academic Medical Center University Hospital;

    Department of Urology, Academic Medical Center University Hospital;

    Department of Urology, Jeroen Bosch Hospital;

    Department of Urology, Jeroen Bosch Hospital;

    Laboratory of Biomedical Diagnostics, Department of Electrical Engineering, Eindhoven University of Technology,Department of Urology, Academic Medical Center University Hospital;

    Laboratory of Biomedical Diagnostics, Department of Electrical Engineering, Eindhoven University of Technology;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Prostate cancer; Diagnostic imaging; Validation studies as topic; Histology; Review;

    机译:前列腺癌;诊断影像;验证研究;组织学;综述;
  • 入库时间 2022-08-17 23:26:26

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