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首页> 外文期刊>Journal of water resource and protection >Detection of Human Pharmaceuticals in the Surface Water of East Fork Stones River
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Detection of Human Pharmaceuticals in the Surface Water of East Fork Stones River

机译：东叉石河地表水中人类药物的检测

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Pharmaceuticals have been detected nationwide in different environmental matrices including wastewater effluents and surface water. In recent studies, pharmaceuticals have also been found in aquatic plants, fish tissues and plasma of shark bulls. Pharmaceuticals that were detected as indicated in published literature, included steroids, prescription drugs such as antibiotics, anti-depressants, anti-inflammatory drugs, hormones and over the counter (OTC) drugs. We conducted a monitoring study to detect the presence of pharmaceuticals in East fork of the Stones River located in Rutherford County in Middle Tennessee. East Fork Stones River is a six (6) order river that drains a large portion of Rutherford County including Murfreesboro, Tennessee. Grab water samples were collected from Stones River for three seasons: (summer and fall of 2014 and 2015 and winter of 2015 and 2016) each year. Water quality parameters were also determined in situ using Eureka Water Probes™ multi-parameter sondes. Water samples were analyzed for the presence of pharmaceutical compounds using GC-MS. Chemical Abstract Service Registry Numbers (CASRN or CAS) for detected pharmaceuticals were identified. Pharmaceuticals detected included those used for treatment of chronic alcoholism (Disulfiram: CAS # 97-77-8), a compound (Thiazoli-dine: CAS # 504-78-9) in the drug Thiazolidinedione which is used for the treatment of type II diabetes, a compound associated with the prevention of anti-inflammatory conditions (Methyl palmitate: CAS # 112-39-0), and emollient in skincare (Undecane: CAS # 1120-21-4). While the quantitative concentrations of these drugs were not determined in this study, their qualitative presence in surface water is noteworthy.
机译：全国范围内已在各种环境基质中检测到药品，包括废水和地表水。在最近的研究中，在水生植物，鱼类组织和鲨鱼公牛的血浆中也发现了药物。如已发表的文献中所述，检测到的药物包括类固醇，处方药（例如抗生素），抗抑郁药，抗炎药，激素和非处方（OTC）药物。我们进行了一项监测研究，以检测位于田纳西州中部卢瑟福县的斯通兹河东叉的药品。东福克斯石头河是一条六（6）阶的河流，排水了卢瑟福县的大部分地区，包括田纳西州的默弗里斯伯勒。每年从斯通斯河（Stones River）收集三个季节的抓水样品：（2014年和2015年夏季和秋季，2015年和2016年冬季）。还使用Eureka Water Probes™多参数探空仪原位确定水质参数。使用GC-MS分析水样品中是否存在药物化合物。确定了所检测药物的化学文摘社注册号（CASRN或CAS）。检出的药物包括用于治疗慢性酒精中毒的药物（二硫仑：CAS＃97​​-77-8），一种噻唑烷二酮中的化合物（噻唑烷二胺：CAS＃504-78-9），用于治疗II型糖尿病，一种与抗炎病症的预防相关的化合物（棕榈酸甲酯：CAS＃112-39-0），在皮肤护理中具有润肤作用（十一烷：CAS＃1120-21-4）。尽管在这项研究中未确定这些药物的定量浓度，但值得注意的是它们在地表水中的定性存在。

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