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首页> 外文期刊>Key Engineering Materials >Fabrication and Biocompatibility of Gradient Bioceramic Coatings on Titanium Alloy Substrate by Laser Cladding
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Fabrication and Biocompatibility of Gradient Bioceramic Coatings on Titanium Alloy Substrate by Laser Cladding

机译：钛合金基体上激光熔覆梯度生物陶瓷涂层的制备及其生物相容性

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摘要

Based on a high power CO_2 laser beam passing by pyramid polygon mirror, the bioceramic coatings of gradient composition were fabricated on titanium alloy substrate (Ti-6Al-4V). The relations among laser processing parameters, microstructure and biocompatibility of the gradient bioceramic coatings were investigated. The results indicated that the contents of rare earth oxide additions had an immediate effect on the formation of bioactive phases. The gradient bioceramic coatings showed favorable biocompatibility in vivo after they were implanted into canine femur for 45, 90, and 180 days, respectively. The bioceramic coatings of Ca/P=1.4 and 0.6wt.% Y_2O_3 totally combined with new bones merely implanted for 45 days. Furthermore, the MTT (Methyl Thiazolyl Tetrazolium) colorimetry results of cell proliferation demonstrated that the cell growth distinctly increased on the gradient bioceramic coatings by laser cladding compared with the un-treated titanium alloy substrate.
机译：以高功率CO_2激光束通过金字塔多角镜为基础，在钛合金基体（Ti-6Al-4V）上制备了梯度成分的生物陶瓷涂层。研究了梯度生物陶瓷涂层的激光加工参数，微观结构和生物相容性之间的关系。结果表明，稀土氧化物添加物的含量对生物活性相的形成具有直接影响。梯度生物陶瓷涂层分别在犬股骨中植入45天，90天和180天后显示出良好的体内生物相容性。 Ca / P = 1.4和0.6wt。％Y_2O_3的生物陶瓷涂层与仅植入45天的新骨骼完全结合在一起。此外，细胞增殖的MTT（甲基噻唑基四唑）比色法结果表明，与未经处理的钛合金基底相比，通过激光熔覆在梯度生物陶瓷涂层上细胞生长明显增加。

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