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Diagnostic Difficulties in Diffuse Xanthogranulomatous Pyelonephritis: A Case Report and Review of the Literature

机译:弥漫性黄原体肉芽肿性肾盂肾炎的诊断困难:一例报道并文献复习

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摘要

Xanthogranulomatous pyelonephritis is a rare, severe, and chronic infection of the kidney characterized by the replacement of renal parenchyma by the xanthoma cells which is difficult to diagnose radiologically. We report a 40-year-old male who had vague abdominal mass and fever for more than 2 months. Weight loss and fatigue were the associated symptoms. Ultrasonography revealed a grossly enlarged right kidney with replacement of renal parenchyma by multiple hypoechoic areas with perinephric thickening and a large staghorn calculus. An abdominal computed tomogram demonstrated an irregular, enlarged right kidney with multiple low-density round areas and calculi. Diminished excretion of contrast media and a severe perinephric inflammatory reaction were present. A presurgical diagnosis of xanthogranulomatous pyelonephritis was made. First, drainage of the extrarenal abscess under proper antibiotic coverage was done and later, a two stage nephrectomy was done considering the debilitating condition of the patient.
机译:黄褐肉瘤性肾盂肾炎是一种罕见,严重和慢性的肾脏感染,其特征是黄瘤细胞替代了肾实质,这在放射学上难以诊断。我们报告了一名40岁的男性,腹部质量模糊,发烧超过2个月。体重减轻和疲劳是相关的症状。超声检查显示右肾明显肿大,肾实质被多个低回声区域代替,并伴有肾周增厚和大鹿角结石。腹部计算机断层扫描显示右肾不规则,增大,有多个低密度的圆形区域和结石。存在造影剂排泄减少和严重的会阴肾炎反应。进行了黄原发性肾盂肾炎的术前诊断。首先,在适当的抗生素覆盖下引流肾外脓肿,然后考虑到患者的虚弱情况,进行了两期肾切除术。

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