Dimethyl fumarate - the background

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Dimethyl fumarate - the background

机译：富马酸二甲酯-背景

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Fungicides and mould inhibiting chemicals play an important role in the production and distribution of leather and leather products. Standard leather-processing fungicides, such as TCMTB (2-(Thiocyanato-methylthio)-l,3-benzothia-zole)), OPP (ortho-phenyl phenol) and OIT (2-n-octyl-4-isoth-iazolin-3-one) are added to prevent mould growth during the wet-blue stage. These chemicals are added and are present in the substrate itself, and allow for transport of the wet-blue without the associated risk of mould growth. In general, fungicides interfere with the germination and penetration process of mould into leather or inhibit fungal growth and reproduction. More specifically, fungicides may interfere with cell division, may inhibit the activity of certain enzymes, or may alter the function of cell membranes.

机译：杀菌剂和抑制霉菌的化学物质在皮革和皮革制品的生产和分销中起着重要作用。标准的皮革加工杀菌剂，例如TCMTB（2-（硫氰酸根合-甲硫基）-1,3-苯并噻唑-唑），OPP（邻苯基苯酚）和OIT（2-正辛基-4-异噻唑啉-加入3-one）以防止在蓝湿阶段霉菌生长。这些化学物质被添加并存在于基材本身中，并且允许湿蓝的运输而没有霉菌生长的相关风险。通常，杀真菌剂会干扰霉菌发芽和渗入皮革的过程或抑制真菌的生长和繁殖。更具体地，杀真菌剂可干扰细胞分裂，可抑制某些酶的活性，或可改变细胞膜的功能。

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《Leather International》 |2009年第4793期|28-29|共2页
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BLC Leather Technology Centre Ltd;
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1. Dimethyl Fumarate Targets MSK1, RSK1, 2 and IKKα/β Kinases and Regulates NF-κB /p65 Activation in Psoriasis: A Demonstration of the Effect on Peripheral Blood Mononuclear Cells, Drawn from Two Patients with Severe Psoriasis Before and After Treatment with Dimethyl Fumarate [J] . Borbala Gesser, Mads K Rasmussen, Lars Iversen Psoriasis: Targets and Therapy . 2020,第12期

机译：二甲基富马酸酯靶向MSK1，RSK1,2和IKKα/β激酶，并调节牛皮癣中的NF-κB/ p65活化：对外周血单核细胞的影响，从两种患者用两种患者用二甲基富马酸盐处理
2. Correlation between lesion site and concentration of dimethyl fumarate in different parts of shoes in patients with contact dermatitis caused by dimethyl fumarate in footwear. [J] . Toledo F, Silvestre JF, Cuesta L, Contact dermatitis . 2011,第2期

机译：鞋类富马酸二甲酯引起的接触性皮炎患者皮损部位与富马酸二甲酯浓度之间的相关性。
3. Improved gastrointestinal profile with diroximel fumarate is associated with a positive impact on quality of life compared with dimethyl fumarate: results from the randomized, double-blind, phase III EVOLVE-MS-2 study [J] . Annette Wundes, Sibyl Wray, Ralf Gold, Therapeutic advances in neurological disorders. . 2021,第a期

机译：改进肺炎米霉素的胃肠道曲线与对生活质量的积极影响有关，与二甲基富马酸盐相比：随机，双盲，III型进化 - MS-2研究结果
4. Synthesis and Characterization of Novel Injectable, Biodegradable and In situ Crosslinkable Poly(hexamethylene-carbonate-fumarate), Poly(hexamethylene carbonate) Diacrylate and Poly(ethylene glycol fumarate-co-hexamethylene carbonate-fumarate) Scaffolds [C] . Sharifi, S., Mirzadeh, Engineering in Medicine and Biology Society, 2006 Annual International Conference of the IEEE . 2006

机译：新型可注射，可生物降解和原位交联的聚（碳酸六亚甲基酯-富马酸酯），聚（碳酸六亚甲基酯）二丙烯酸酯和聚（乙二醇富马酸酯-碳酸六亚甲基酯-富马酸酯）支架的合成与表征
5. Analysis of intermolecular interaction of dimethyl sulphoxide and dimethyl formamide solvates of febuxostat by thermal and spectral methods. [D] . Mahamuni, Rutuja Suhas. 2016

机译：通过热和光谱方法分析非布索坦的二甲亚砜和二甲基甲酰胺溶剂化物的分子间相互作用。
6. Dimethyl Fumarate Targets MSK1 RSK1 2 and IKKα/β Kinases and Regulates NF-κB /p65 Activation in Psoriasis: A Demonstration of the Effect on Peripheral Blood Mononuclear Cells Drawn from Two Patients with Severe Psoriasis Before and After Treatment with Dimethyl Fumarate [O] . Borbala Gesser, Mads K Rasmussen, Lars Iversen 2020

机译：富马酸二甲酯靶向MSK1RSK1、2和IKKα/β激酶并调节银屑病中的NF-κB/ p65活化：证实了富马酸二甲酯治疗前后对两名患有严重牛皮癣的患者的外周血单个核细胞的影响
7. >Dimethyl Fumarate Targets MSK1, RSK1, 2 and IKKα/β Kinases and Regulates NF-κB /p65 Activation in Psoriasis: A Demonstration of the Effect on Peripheral Blood Mononuclear Cells, Drawn from Two Patients with Severe Psoriasis Before and After Treatment with Dimethyl Fumarate [O] . Borbala Gesser, Mads K Rasmussen, Lars Iversen 2020

机译：>富马酸核苷酸靶MSK1，RSK1,2和IKKα/β激酶并调节牛皮癣中的NF-κB/ p65活化：对外周血单核细胞的影响的证明，从两次治疗前后的严重牛皮癣患者吸取二甲基富马酸盐

Dimethyl fumarate - the background

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