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Titanium dioxide-cellulose hybrid nanocomposite and its glucose biosensor application

机译:二氧化钛-纤维素杂化纳米复合材料及其葡萄糖生物传感器的应用

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This paper investigates the fabrication of titanium dioxide (TiO_2)-cellulose hybrid nanocomposite and its possibility for a conductometric glucose biosensor. TiO_2 nanoparticles were blended with cellulose solution prepared by dissolving cotton pulp with lithium chloride/AUV-dimethylacetamide solvent to fabricate TiO_2-cellulose hybrid nanocomposite. The enzyme, glucose oxidase (GOx) was immobilized into this hybrid nanocomposite by physical adsorption method. The successful immobilization of glucose oxidase into TiO_2-cellulose hybrid nanocomposite via covalent bonding between TiO_2 and GOx was confirmed by X-ray photoelectron analysis. The linear response of the glucose biosensor is obtained in the range of 1-10mM. This study demonstrates that TiO_2-cellulose hybrid nanocomposite can be a potential candidate for an inexpensive, flexible and disposable glucose biosensor.
机译:本文研究了二氧化钛(TiO_2)-纤维素杂化纳米复合材料的制备及其用于电导葡萄糖生物传感器的可能性。将TiO_2纳米颗粒与纤维素溶液混合,该溶液通过将棉浆溶解在氯化锂/ AUV-二甲基乙酰胺溶剂中而制得,从而制备TiO_2-纤维素杂化纳米复合材料。通过物理吸附法将葡萄糖氧化酶(GOx)酶固定在该杂化纳米复合材料中。通过X射线光电子分析证实了通过TiO_2与GOx之间的共价键将葡萄糖氧化酶成功固定在TiO_2-纤维素杂化纳米复合材料中。葡萄糖生物传感器的线性响应在1-10mM的范围内获得。这项研究表明,TiO_2-纤维素杂化纳米复合材料可以成为廉价,灵活和一次性葡萄糖生物传感器的潜在候选者。

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