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首页> 外文期刊>Materials Science and Engineering >Study of nanobiomaterial hydroxyapatite in simulated body fluid: Formation and growth of apatite
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Study of nanobiomaterial hydroxyapatite in simulated body fluid: Formation and growth of apatite

机译：模拟体液中纳米生物材料羟基磷灰石的研究：磷灰石的形成与生长

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Hydroxyapatite (Hap) is main mineral component of hard tissues. It is widely used in biomedical applications due to its excellent bioactivity and biocompatibility. Nanosized Hap is synthesized by wet chemical process. The synthesized Hap is characterized by XRD, FTIR, AFM and SEM for structural, morphological and functional groups analysis. The Simulated Body Fluid (SBF) is prepared by using chlorides, carbonates, oxides, and sulphates of alkali metals at 37℃. The ion exchange process is carried out to exchange calcium cation by sodium and potassium. The pure Hap and ion exchanged Hap pellets are used as source of nucleating agent for apatite layer formation, in SBF maintained at 37℃ using incubator for different periods of time to study the bioactivity. The dielectric study is carried out on incubated pure and ion exchanged Hap pellets. XRD analysis confirms the hexagonal phase of hydroxyapatite. FTIR shows the presence of functional groups. SEM observations reveal that the growth of highly porous apatite layer on Hap surface increases with time. The dielectric constant is found to be in the range 3-12. It is seen that the synthesized Hap bioceramic nano material not only supports the growth of apatite layer but also accelerates the growth onto itself.
机译：羟基磷灰石（Hap）是硬组织的主要矿物质成分。由于其优异的生物活性和生物相容性，它被广泛用于生物医学应用。纳米包装是通过湿化学法合成的。通过XRD，FTIR，AFM和SEM对合成的Hap进行表征，以进行结构，形态和官能团分析。模拟体液（SBF）是在37℃下使用碱金属的氯化物，碳酸盐，氧化物和硫酸盐制备的。进行离子交换过程以通过钠和钾交换钙阳离子。将纯的Hap和离子交换的Hap丸用作磷灰石层形成的成核剂来源，在37℃的SBF中，使用恒温箱在不同的时间段内研究生物活性。介电研究是在培养的纯净和离子交换的Hap沉淀上进行的。 XRD分析证实了羟基磷灰石的六方相。 FTIR显示官能团的存在。 SEM观察表明，Hap表面上高度多孔的磷灰石层的生长随时间增加。介电常数在3-12的范围内。可以看出，合成的Hap生物陶瓷纳米材料不仅支持磷灰石层的生长，而且还促进了自身生长。

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