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Fast-ion transport in peptide nanochannels

机译:肽纳米通道中的快速离子转运

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摘要

This review summarizes recent results of the ion transport in narrow peptide nanochannels (PNCs) conducting ions and water molecules at various densities. The molecular structure of the nanochannel is a periodic continuation of the short selectivity pore of a biological potassium channel. The ion conductivity of a PNC can reach ion velocities up to 50 m/s. This phenomena is based on a fine tuned interplay between the three constituents of the PNC: the ions, the water molecules, and the flexible carbonyl groups of the channel's backbone, which represents a one-dimensional fluctuating lattice potential for ions and water. The unidirectional transport is based on hopping processes of bound ion-water pairs ('permons') mediated by the lattice potential.
机译:这篇综述总结了在各种密度下传导离子和水分子的窄肽纳米通道(PNC)中离子迁移的最新结果。纳米通道的分子结构是生物钾通道的短选择性孔的周期性延续。 PNC的离子电导率可以达到高达50 m / s的离子速度。这种现象基于PNC的三个组成部分之间的微调相互作用:离子,水分子和通道主干的柔性羰基,这表示离子和水的一维波动晶格势。单向传输基于晶格势介导的结合的离子水对(“ permons”)的跳跃过程。

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