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首页> 外文期刊>Materials Science and Engineering >Antibacterial activity of Ag nanoparticles/phosphomolybdate/reduced graphene oxide nanocomposite: Kinetics and mechanism insights
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Antibacterial activity of Ag nanoparticles/phosphomolybdate/reduced graphene oxide nanocomposite: Kinetics and mechanism insights

机译：Ag纳米粒子/磷钼皂酯/氧化石墨烯纳米复合材料的抗菌活性：动力学和机制见解

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摘要

For the first time, Ag nanoparticles/phosphomolybdate/reduced graphene oxide (Ag/PMo/RGO) nanocomposite was prepared and its antibacterial activity against Escherichia coli (E. coli) was assessed by the minimum inhibitory concentration (MIC), the minimum bactericidal concentration (MBC), time-killing curve, and the morphology of the bacteria before and after exposure to Ag/PMo/RGO. The MIC and MBC values of the nanocomposite were measured as 256 and 512 μg/mL, respectively. Since the ratio of MBC to MIC of Ag/PMo/RGO was less than 4, it could be considered as a bactericidal agent. The MIC value of the Ag/PMo/RGO is 256 μg/mL which is 15.31 and 7.66 times less than those of PMo (3920 μg/mL) and PMo/RGO (512 μg/mL), respectively. Hence, Ag/PMo/RGO exhibited superior antibacterial efficiency compared with those of PMo and PMo/RGO. The results showed that the cytotoxicity of Ag/PMo/RGO depends on time as well as the concentration of the nanocomposite.
机译：首次，制备Ag纳米颗粒/磷钼/氯钼/氧化石墨烯（Ag / PMO / Rgo）纳米复合材料，并通过最小抑制浓度（MIC），最小杀菌浓度评估其对大肠杆菌（大肠杆菌）的抗菌活性（MBC），时间杀伤曲线，以及暴露于AG / PMO / RGO之前和之后的细菌的形态。将纳米复合材料的MIC和MBC值分别测量为256和512μg/ mL。由于AG / PMO / RGO的MBC与MIC的比率小于4，因此可以认为是杀菌剂。 AG / PMO / RGO的MIC值为256μg/ mL，分别比PMO（3920μg/ mL）和PMO / RGO（512μg/ mL）小于15.31和7.66倍。因此，与PMO和PMO / RGO相比，AG / PMO / Rgo表现出优异的抗菌效率。结果表明，Ag / PMO / RGO的细胞毒性取决于时间和纳米复合材料的浓度。

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