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首页> 外文期刊>Materials science & engineering >Bioactive multi-elemental PEO-coatings on titanium for dental implant applications
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Bioactive multi-elemental PEO-coatings on titanium for dental implant applications

机译：用于牙科植入物的钛生物活性多元PEO涂层

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摘要

Bioactive PEO (Plasma Electrolytic Oxidation) coatings were generated on Grade I commercially pure titanium for dentistry applications using a Ca/P-based electrolyte with added Si, Mg, Zn or F species. Surface characteristics, chemical composition and ion liberation of the coatings were characterized using SEM/EDS, X-ray diffraction, optical profilometry, contact angle and ICP-OES. Corrosion resistance (OCP and DC polarization) was evaluated in SBF. Osteoblastogenesis and osteoclastogenesis processes on PEO-coated Ti and non-coated Ti controls were assessed after 7 days and 5 days of cell culture, respectively. Monolayer formation and metabolic activity were evaluated for the MC3T3 preosteoblastic cell line. All PEO coatings favoured differentiation processes over proliferation and presented three times greater quantity of secreted collagen than non-coated Ti control. All coating enabled osteoclast differentiation, with differences in number and size of the osteoclasts between the materials.
机译：使用具有添加的Si，Mg，Zn或F种类的基于Ca / P的电解质，在I级商业纯钛上生成生物活性PEO（等离子电解氧化）涂层，用于牙科应用。使用SEM / EDS，X射线衍射，光学轮廓，接触角和ICP-OES对涂层的表面特性，化学组成和离子释放进行了表征。在SBF中评估了耐腐蚀性（OCP和DC极化）。在细胞培养7天和5天后，分别评估了PEO包被的Ti和未包被的Ti对照的成骨细胞生成和破骨细胞生成过程。评价了MC3T3成骨前细胞细胞系的单层形成和代谢活性。所有的PEO涂层都比分化过程更倾向于分化过程，并且分泌的胶原蛋白量是未涂层的Ti对照的三倍。所有涂层都能使破骨细胞分化，材料之间的破骨细胞数量和大小也不同。

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  • 来源
    《Materials science & engineering》 |2019年第4期|738-752|共15页
  • 作者

    Santos-Coquillat A.; Mohedano M.; Martinez-Campos E.; Arrabal R.; Pardo A.; Matykina E.;

  • 作者单位

    Univ Complutense, Fac Ciencias Quim, Dept Ingn Quim & Mat, E-28040 Madrid, Spain|UCM, Inst Biofunct Studies IEB, Associated Unit Inst Polymer Sci & Technol CSIC, Tissue Engn Grp,Polymer Functionalizat Grp, Madrid 28040, Spain;

    Univ Complutense, Fac Ciencias Quim, Dept Ingn Quim & Mat, E-28040 Madrid, Spain;

    UCM, Inst Biofunct Studies IEB, Associated Unit Inst Polymer Sci & Technol CSIC, Tissue Engn Grp,Polymer Functionalizat Grp, Madrid 28040, Spain|UCM, IEB, Inst Biofunct Studies, Paseo Juan XXIII 1, Madrid 28040, Spain;

    Univ Complutense, Fac Ciencias Quim, Dept Ingn Quim & Mat, E-28040 Madrid, Spain;

    Univ Complutense, Fac Ciencias Quim, Dept Ingn Quim & Mat, E-28040 Madrid, Spain;

    Univ Complutense, Fac Ciencias Quim, Dept Ingn Quim & Mat, E-28040 Madrid, Spain|UCM, IEB, Inst Biofunct Studies, Paseo Juan XXIII 1, Madrid 28040, Spain;

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  • 正文语种 eng
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  • 关键词

    Surface modification; Plasma electrolytic oxidation; Bioactive coating; Titanium implant; Osteoblast; Osteoclast;

    机译：表面改性;等离子电解氧化;生物活性涂层;钛植入物;成骨细胞;破骨细胞;

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