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Can bioactive glasses be useful to accelerate the healing of epithelial tissues?

机译:生物活性玻璃可以用于促进上皮组织的愈合吗?

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摘要

Over the last decade, there has been an impressive growth of new potential applications for bioactive glasses (BGs) in regenerative medicine. Apart from being used in contact with injured bone, BGs are now showing promise in accelerating the healing of soft tissues too, such as epithelium, thus creating new hopes for the repair of damaged skin, gastrointestinal tract and airspaces of the lungs. BGs can form a biological bond with soft tissues, accelerate epithelial cell proliferation, and reduce the inflammation in the injured sites. BGs can also be added to "soft" polymeric matrices for imparting biological extra-functionalities (e.g. enhanced angiogenesis) which play a key role in epithelial reconstruction strategies. The aim of this study is to provide a critical review of the potential of various types of BGs for the repair and regeneration of the epithelial tissues based on the existing data in the literature.
机译:在过去的十年中,再生医学中生物活性玻璃(BG)的新潜在应用有了惊人的增长。除了用于与受伤的骨头接触之外,BG现在也显示出在加速软组织(如上皮)愈合方面的前景,从而为修复受损的皮肤,胃肠道和肺部空域创造了新的希望。 BG可与软组织形成生物键,加速上皮细胞增殖,并减轻受伤部位的炎症。还可以将BG添加到“软”聚合物基质中以赋予生物学上的额外功能(例如,增强的血管生成),其在上皮重建策略中起关键作用。这项研究的目的是根据文献中的现有数据,对各种类型的BG在修复和再生上皮组织方面的潜力提供重要的评论。

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