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Spinel ferrite nanoparticles and nanocomposites for biomedical applications and their toxicity

机译:尖晶石型铁氧体纳米颗粒和纳米复合材料的生物医学应用及其毒性

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摘要

This review focuses on the biomedical applications and toxicity of spinel ferrite nanoparticles (SFNPs) with more emphasis on the recently published work. A critical review is provided on recent advances of SFNPs applications in biomedical areas. The novelty of SFNPs in addressing the bottleneck problems encountered in the areas of health; in particular, for diagnosis and treatment of tumour cells are well reviewed. Furthermore, research gaps, toxicity of SFNPs and areas which still need more attention are highlighted. Based on the result of this review, the SFNPs have unlimited capacity in cancer treatment, disease diagnosis, magnetic resonance imaging, drug delivery and release. Overall, stepping out of the conventional way of treatment is difficult but also essential in bringing long lasting solution for cancer and other diseases treatment. In fact, the toxicity study and commercialisation of the SFNPs based cancer treatment options are the main challenges and need further study, in order to reduce unforeseen consequences.
机译:这篇评论集中在尖晶石铁氧体纳米颗粒(SFNPs)的生物医学应用和毒性,而更多地侧重于最近发表的工作。对SFNPs在生物医学领域的最新进展进行了严格的审查。 SFNP在解决卫生领域遇到的瓶颈问题方面的新颖性;特别地,对于肿瘤细胞的诊断和治疗已经进行了很好的综述。此外,突出了研究差距,SFNPs的毒性以及仍需进一步关注的领域。根据审查的结果,SFNP在癌症治疗,疾病诊断,磁共振成像,药物输送和释放方面具有无限的能力。总体而言,要摆脱传统的治疗方式是困难的,但对于带来持久的癌症和其他疾病治疗解决方案也是必不可少的。实际上,基于SFNPs的癌症治疗方案的毒性研究和商业化是主要挑战,需要进行进一步研究,以减少无法预料的后果。

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