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首页> 外文期刊>Materials science & engineering >Spider (Linothele megatheloides) and silkworm (Bombyx mori) silks: Comparative physical and biological evaluation
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Spider (Linothele megatheloides) and silkworm (Bombyx mori) silks: Comparative physical and biological evaluation

机译：蜘蛛丝（Linothele megatheloides）和蚕丝（Bombyx mori）：比较的物理和生物学评价

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摘要

Silks, in particular silkworm silks, have been studied for decades as possible candidate materials for biomedical applications. Recently, great attentions have been paid to spider silks, mainly due to their unique and remarkable mechanical properties. Both materials express singular interactions with cells through specific biorecognition moieties on the core proteins making up the two silks. In this work, the silk from a Colombian spider, Linothele megadieloides (LM), which produces a single type of silk in a relatively large amount, was studied in comparison with silk from Bombyx mod silkworm, before and after degumming, with the evaluation of their chemical, mechanical and biological properties. Unexpected biological features in cell culture tests were found for the LM silk already at very early stage, so suggesting further investigation to explore its use for tailored biomedical applications.
机译：丝绸，特别是蚕丝，已经被研究了数十年，可能作为生物医学应用的候选材料。最近，蜘蛛丝受到了极大的关注，这主要是由于其独特而卓越的机械性能。两种材料都通过构成两条丝的核心蛋白上的特定生物识别部分表达与细胞的奇异相互作用。在这项工作中，与来自Bombyx mod蚕的脱胶前后相比，研究了哥伦比亚蜘蛛Linothele megadieloides（LM）产生的蚕丝，该蚕产生了相对大量的单一类型的蚕丝。它们的化学，机械和生物学特性。在很早的阶段就已经在LM丝的细胞培养测试中发现了意外的生物学特征，因此建议进行进一步研究以探索其在定制生物医学应用中的用途。

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  • 来源
    《Materials science & engineering》 |2020年第2期|110197.1-110197.10|共10页
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  • 作者单位

    Univ Trento Dept Ind Engn Trento Italy|Univ Trento BIOtech Res Ctr Trento Italy|European Inst Excellence Tissue Engn & Regenerat Trento Unit Trento Italy;

    Univ Trento Dept Civil Environm & Mech Engn Lab Bioinspired & Graphene Nanomech Trento Italy|Ist Italia Tecnol Ctr Micro BioRobot SSSA Genoa Italy;

    Ist Italia Tecnol Ctr Micro BioRobot SSSA Genoa Italy;

    Univ Trento Dept Civil Environm & Mech Engn Lab Bioinspired & Graphene Nanomech Trento Italy|Queen Mary Univ London Sch Engn & Mat Sci London England|Edoardo Amaldi Fdn Ket Lab Bologna Italy;

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  • 正文语种 eng
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  • 关键词

    Spider silk; Linothele megatheloides; Bombyx most silk; Natural polymer; Cell adhesion; Bioactivity;

    机译：蜘蛛丝;Linothele megatheloides;家蚕最蚕丝;天然聚合物;细胞粘附;生物活性;

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