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Easy synthesis of highly fluorescent carbon dots from albumin and their photoluminescent mechanism and biological imaging applications

机译:从白蛋白容易合成高荧光碳点及其光致发光机理和生物成像应用

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摘要

A simple and green approach was developed to synthesize highly fluorescent carbon dots (CDs) using albumin as a carbon source in aqueous solution at room temperature. The CDs were characterized by excellent monodispersion, superior photostability, pH-independent emission, long fluorescence lifetime and high quantum yield (QY). The photoluminescent (PL) mechanism of CDs was explored by means of time-resolved PL decay, and the results revealed that PL originated from the emission of both defect state and intrinsic state. In addition, biological imaging with the application of CDs was carried out in human breast cancer Bcap-37 cell, which demonstrated that CDs were provided with an excellent biocompan'blity, low cytotoxicity and good transmembrane ability. Besides, CDs could be considered as a potential substitute for organic dyes or semiconductor quantum dots (SQDs) in biological imaging.
机译:开发了一种简单而绿色的方法来在室温下使用白蛋白作为水溶液中的碳源来合成高荧光碳点(CD)。 CD具有出色的单分散性,出色的光稳定性,不受pH限制的发射,长荧光寿命和高量子产率(QY)的特点。通过时间分辨的PL衰变探索了CD的光致发光(PL)机理,结果表明PL起源于缺陷态和固有态的发射。另外,在人乳腺癌Bcap-37细胞中进行了CDs生物学成像,证明CDs具有良好的生物相容性,低细胞毒性和良好的跨膜能力。此外,在生物成像中,CD可被视为有机染料或半导体量子点(SQD)的潜在替代品。

著录项

  • 来源
    《Materials science & engineering》 |2016年第1期|730-736|共7页
  • 作者

    Xiaohua Hu; Xueqin An; Lielie Li;

  • 作者单位

    School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China;

    School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China;

    School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Carbon dots; Novel synthesis method; Photoluminescent mechanism; Biological imaging;

    机译:碳点;新颖的合成方法;发光机理;生物成像;

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