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首页> 外文期刊>Materials science & engineering >Sunflower oil mediated biomimetic synthesis and cytotoxicity of monodisperse hexagonal silver nanoparticles
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Sunflower oil mediated biomimetic synthesis and cytotoxicity of monodisperse hexagonal silver nanoparticles

机译：葵花油介导的仿生六方银纳米颗粒的仿生合成和细胞毒性

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In this work, sunflower oil was utilized for the biomimetic synthesis of silver (Ag) nanoparticles (NPs), leading to highly mono-dispersed hexagonal-shaped silver nanoparticles (NPs) at various concentrations. It was found that the biomolecules of the oil not only have the capability to reduce silver ions, due to its extended phenolic system, but also appear to recognize and affect the Ag nanocrystal growth on the (110) face, leading to hexagonal growth of the NPs of 50 nm size. Initially, some spherical AgNPs of less than 10 nm diameter were observed; however, over a longer period of time, a majority of hexagonal-shaped nanocrystals were formed. The one step synthesis can be extended for other metals. The as prepared sunflower oil capped AgNPs being completely free of toxic chemicals can be directly utilized for in vitro studies and offer a more rational approach for cellular applications. The NP solution exhibited dose-dependent cytotoxicity in human lung carcinoma cells and physiologically relevant cell model (3T3L1cells).
机译：在这项工作中，葵花籽油用于银（Ag）纳米颗粒（NPs）的仿生合成，从而导致各种浓度的高度单分散的六边形银纳米颗粒（NPs）。发现该油的生物分子不仅由于其扩展的酚醛体系而具有还原银离子的能力，而且还似乎识别并影响（110）面上的Ag纳米晶体的生长，从而导致该化合物的六角形生长。 50 nm大小的NP。最初，观察到一些直径小于10 nm的球形AgNP。然而，在较长的时间内，形成了大多数六边形的纳米晶体。一步合成可以扩展到其他金属。完全不含毒性化学物质的已制备向日葵油封端的AgNPs可直接用于体外研究，并为细胞应用提供了更合理的方法。 NP溶液在人肺癌细胞和生理相关细胞模型（3T3L1细胞）中表现出剂量依赖性的细胞毒性。

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