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Fabrication of porous titanium scaffold with controlled porous structure and net-shape using magnesium as spacer

机译：以镁为间隔物制备具有可控的多孔结构和网状的多孔钛支架

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摘要

This paper reports a new approach to fabricating biocompatible porous titanium with controlled pore structure and net-shape. The method is based on using sacrificial Mg particles as space holders to produce compacts that are mechanically stable and machinable. Using magnesium granules and Ti powder, Ti/Mg compacts with transverse rupture strength (～85 MPa) sufficient for machining were fabricated by warm compaction, and a complex-shape Ti scaffold was eventually produced by removal of Mg granules from the net-shape compact The pores with the average size of 132-262 μm were well distributed and interconnected. Due to anisotropy and alignment of the pores the compressive strength varied with the direction of compression. In the case of pores aligned with the direction of compression, the compressive strength values (59-280 MPa) high enough for applications in load bearing implants were achieved. To verify the possibility of controlled net-shape, conventional machining process was performed on Ti/Mg compact. Compact with screw shape and porous Ti scaffold with hemispherical cup shape were fabricated by the results. Finally, it was demonstrated by cell tests using MC3T3-E1 cell line that the porous Ti scaffolds fabricated by this technique are biocompatible.
机译：本文报道了一种新的制备具有可控孔结构和净形的生物相容性多孔钛的方法。该方法基于使用牺牲的Mg颗粒作为空间保持器来生产机械稳定且可加工的压坯。使用镁颗粒和Ti粉，通过热压制成具有足以进行机械加工的横向断裂强度（〜85 MPa）的Ti / Mg压块，最后通过从网状压块中除去Mg颗粒最终制成复杂形状的Ti支架平均大小为132-262μm的孔分布均匀且相互连通。由于孔的各向异性和排列，抗压强度随压缩方向而变化。在孔与压缩方向对齐的情况下，获得了足够高的抗压强度值（59-280 MPa），可用于承重植入物。为了验证可控网状形状的可能性，对Ti / Mg压块进行了常规加工。结果制得螺旋形致密体和半球形杯状多孔Ti支架。最后，通过使用MC3T3-E1细胞系的细胞测试证明，通过该技术制造的多孔Ti支架具有生物相容性。

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  • 来源
    《Materials science & engineering》 |2013年第5期|2808-2815|共8页
  • 作者

    Sung Won Kim; Hyun-Do Jung; Min-Ho Kang; Hyoun-Ee Kim; Young-Hag Koh; Yuri Estrin;

  • 作者单位

    Department of Materials Science and Engineering, Seoul National University, Seoul, 151-742, Republic of Korea;

    Department of Materials Science and Engineering, Seoul National University, Seoul, 151-742, Republic of Korea;

    Department of Materials Science and Engineering, Seoul National University, Seoul, 151-742, Republic of Korea;

    Department of Materials Science and Engineering, Seoul National University, Seoul, 151-742, Republic of Korea;

    Department of Dental Laboratory Science and Engineering, Korea University, Seoul 136-703, Republic of Korea;

    Centre for Advanced Hybrid Materials, Department of Materials Engineering, Monash University, Clayton, Australia;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Titanium; Magnesium; Porous metal; Space holder method; Complex shape;

    机译：钛;镁;多孔金属占位符方法;形状复杂;

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